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Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner.
Kato M, Placencio-Hickok VR, Madhav A, Haldar S, Tripathi M, Billet S, Mishra R, Smith B, Rohena-Rivera K, Agarwal P, Duong F, Angara B, Hickok D, Liu Z, Bhowmick NA. Kato M, et al. Among authors: angara b. Oncogene. 2019 Jan;38(5):716-730. doi: 10.1038/s41388-018-0461-3. Epub 2018 Sep 3. Oncogene. 2019. PMID: 30177832 Free PMC article.
Antagonizing CD105 enhances radiation sensitivity in prostate cancer.
Madhav A, Andres A, Duong F, Mishra R, Haldar S, Liu Z, Angara B, Gottlieb R, Zumsteg ZS, Bhowmick NA. Madhav A, et al. Among authors: angara b. Oncogene. 2018 Aug;37(32):4385-4397. doi: 10.1038/s41388-018-0278-0. Epub 2018 May 2. Oncogene. 2018. PMID: 29717261 Free PMC article.
Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance.
Haldar S, Mishra R, Billet S, Thiruvalluvan M, Placencio-Hickok VR, Madhav A, Duong F, Angara B, Agarwal P, Tighiouart M, Posadas EM, Bhowmick NA. Haldar S, et al. Among authors: angara b. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8515-8523. doi: 10.1073/pnas.1910952117. Epub 2020 Apr 1. Proc Natl Acad Sci U S A. 2020. PMID: 32238563 Free PMC article.
Antagonizing CD105 and androgen receptor to target stromal-epithelial interactions for clinical benefit.
Smith BN, Mishra R, Billet S, Placencio-Hickok VR, Kim M, Zhang L, Duong F, Madhav A, Scher K, Moldawer N, Oppenheim A, Angara B, You S, Tighiouart M, Posadas EM, Bhowmick NA. Smith BN, et al. Among authors: angara b. Mol Ther. 2023 Jan 4;31(1):78-89. doi: 10.1016/j.ymthe.2022.08.019. Epub 2022 Aug 31. Mol Ther. 2023. PMID: 36045587 Free PMC article.