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Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine.
Tumiatti V, Rosini M, Bartolini M, Cavalli A, Marucci G, Andrisano V, Angeli P, Banzi R, Minarini A, Recanatini M, Melchiorre C. Tumiatti V, et al. Among authors: andrisano v. J Med Chem. 2003 Mar 13;46(6):954-66. doi: 10.1021/jm021055+. J Med Chem. 2003. PMID: 12620072
3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
Piazzi L, Rampa A, Bisi A, Gobbi S, Belluti F, Cavalli A, Bartolini M, Andrisano V, Valenti P, Recanatini M. Piazzi L, et al. Among authors: andrisano v. J Med Chem. 2003 Jun 5;46(12):2279-82. doi: 10.1021/jm0340602. J Med Chem. 2003. PMID: 12773032
211 results