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Alpha-synuclein pore forming activity upon membrane association.
Tosatto L, Andrighetti AO, Plotegher N, Antonini V, Tessari I, Ricci L, Bubacco L, Dalla Serra M. Tosatto L, et al. Among authors: andrighetti ao. Biochim Biophys Acta. 2012 Nov;1818(11):2876-83. doi: 10.1016/j.bbamem.2012.07.007. Epub 2012 Jul 20. Biochim Biophys Acta. 2012. PMID: 22820150 Free article.
Perforin activity at membranes leads to invaginations and vesicle formation.
Praper T, Sonnen AF, Kladnik A, Andrighetti AO, Viero G, Morris KJ, Volpi E, Lunelli L, Dalla Serra M, Froelich CJ, Gilbert RJ, Anderluh G. Praper T, et al. Among authors: andrighetti ao. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21016-21. doi: 10.1073/pnas.1107473108. Epub 2011 Dec 15. Proc Natl Acad Sci U S A. 2011. PMID: 22173634 Free PMC article.