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Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation.
Kentala H, Koponen A, Kivelä AM, Andrews R, Li C, Zhou Y, Olkkonen VM. Kentala H, et al. Among authors: andrews r. FASEB J. 2018 Mar;32(3):1281-1295. doi: 10.1096/fj.201700604R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29092904
The results point at a novel function of ORP2 as a lipid-sensing regulator of the actin cytoskeleton, with impacts on hepatocellular migration, adhesion, and proliferation.-Kentala, H., Koponen, A., Kivela, A. M., Andrews, R., Li, C., Zhou, Y., Olkkonen, V. M. Analy …
The results point at a novel function of ORP2 as a lipid-sensing regulator of the actin cytoskeleton, with impacts on hepatocellular migrati …
OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism.
Kentala H, Koponen A, Vihinen H, Pirhonen J, Liebisch G, Pataj Z, Kivelä A, Li S, Karhinen L, Jääskeläinen E, Andrews R, Meriläinen L, Matysik S, Ikonen E, Zhou Y, Jokitalo E, Olkkonen VM. Kentala H, et al. Among authors: andrews r. Cell Mol Life Sci. 2018 Nov;75(21):4041-4057. doi: 10.1007/s00018-018-2850-8. Epub 2018 Jun 12. Cell Mol Life Sci. 2018. PMID: 29947926
Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274.
Meckelmann SW, Hawksworth JI, White D, Andrews R, Rodrigues P, O'Connor A, Alvarez-Jarreta J, Tyrrell VJ, Hinz C, Zhou Y, Williams J, Aldrovandi M, Watkins WJ, Engler AJ, Lo Sardo V, Slatter DA, Allen SM, Acharya J, Mitchell J, Cooper J, Aoki J, Kano K, Humphries SE, O'Donnell VB. Meckelmann SW, et al. Among authors: andrews r. Circ Genom Precis Med. 2020 Jun;13(3):e002806. doi: 10.1161/CIRCGEN.119.002806. Epub 2020 May 12. Circ Genom Precis Med. 2020. PMID: 32396387 Free PMC article.
Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells.
Crittenden S, Goepp M, Pollock J, Robb CT, Smyth DJ, Zhou Y, Andrews R, Tyrrell V, Gkikas K, Adima A, O'Connor RA, Davies L, Li XF, Yao HX, Ho GT, Zheng X, Mair A, Vermeren S, Qian BZ, Mole DJ, Gerasimidis K, Schwarze JKJ, Breyer RM, Arends MJ, O'Donnell VB, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Rossi AG, Howie SE, Yao C. Crittenden S, et al. Among authors: andrews r. Sci Adv. 2021 Feb 12;7(7):eabd7954. doi: 10.1126/sciadv.abd7954. Print 2021 Feb. Sci Adv. 2021. PMID: 33579710 Free PMC article.
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Twohig JP, Cardus Figueras A, Andrews R, Wiede F, Cossins BC, Derrac Soria A, Lewis MJ, Townsend MJ, Millrine D, Li J, Hill DG, Uceda Fernandez J, Liu X, Szomolay B, Pepper CJ, Taylor PR, Pitzalis C, Tiganis T, Williams NM, Jones GW, Jones SA. Twohig JP, et al. Among authors: andrews r. Nat Immunol. 2019 Apr;20(4):458-470. doi: 10.1038/s41590-019-0350-0. Epub 2019 Mar 19. Nat Immunol. 2019. PMID: 30890796 Free PMC article.
1,884 results