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A Deep Learning Approach to Antibiotic Discovery.
Cell. 2020 Apr 16;181(2):475-483. doi: 10.1016/j.cell.2020.04.001.
Cell. 2020.
PMID: 32302574
Free article.
No abstract available.
Targeting Antibiotic Tolerance, Pathogen by Pathogen.
Meylan S, Andrews IW, Collins JJ.
Meylan S, et al. Among authors: andrews iw.
Cell. 2018 Mar 8;172(6):1228-1238. doi: 10.1016/j.cell.2018.01.037.
Cell. 2018.
PMID: 29522744
Free article.
Review.
Item in Clipboard
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria.
Stokes JM, Gutierrez A, Lopatkin AJ, Andrews IW, French S, Matic I, Brown ED, Collins JJ.
Stokes JM, et al. Among authors: andrews iw.
Nat Methods. 2019 Apr;16(4):303-306. doi: 10.1038/s41592-019-0333-y. Epub 2019 Mar 11.
Nat Methods. 2019.
PMID: 30858599
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A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ.
Stokes JM, et al. Among authors: andrews iw.
Cell. 2020 Feb 20;180(4):688-702.e13. doi: 10.1016/j.cell.2020.01.021.
Cell. 2020.
PMID: 32084340
Free PMC article.
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Discovery of antibiotics that selectively kill metabolically dormant bacteria.
Zheng EJ, Valeri JA, Andrews IW, Krishnan A, Bandyopadhyay P, Anahtar MN, Herneisen A, Schulte F, Linnehan B, Wong F, Stokes JM, Renner LD, Lourido S, Collins JJ.
Zheng EJ, et al. Among authors: andrews iw.
Cell Chem Biol. 2024 Apr 18;31(4):712-728.e9. doi: 10.1016/j.chembiol.2023.10.026. Epub 2023 Nov 28.
Cell Chem Biol. 2024.
PMID: 38029756
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Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality.
Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, Collins JJ.
Lobritz MA, et al. Among authors: andrews iw.
Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4. doi: 10.1016/j.chembiol.2021.12.010. Epub 2022 Jan 5.
Cell Chem Biol. 2022.
PMID: 34990601
Free PMC article.
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Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies.
Zheng EJ, Andrews IW, Grote AT, Manson AL, Alcantar MA, Earl AM, Collins JJ.
Zheng EJ, et al. Among authors: andrews iw.
Nat Commun. 2022 May 9;13(1):2525. doi: 10.1038/s41467-022-30272-0.
Nat Commun. 2022.
PMID: 35534481
Free PMC article.
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Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.
Wei H, Volpatti LR, Sellers DL, Maris DO, Andrews IW, Hemphill AS, Chan LW, Chu DS, Horner PJ, Pun SH.
Wei H, et al. Among authors: andrews iw.
Angew Chem Int Ed Engl. 2013 May 10;52(20):5377-81. doi: 10.1002/anie.201301896. Epub 2013 Apr 16.
Angew Chem Int Ed Engl. 2013.
PMID: 23592572
Free PMC article.
No abstract available.
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