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Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population.
Singh A, D'Amico D, Andreux PA, Dunngalvin G, Kern T, Blanco-Bose W, Auwerx J, Aebischer P, Rinsch C. Singh A, et al. Among authors: andreux pa. Eur J Clin Nutr. 2022 Feb;76(2):297-308. doi: 10.1038/s41430-021-00950-1. Epub 2021 Jun 11. Eur J Clin Nutr. 2022. PMID: 34117375 Free PMC article. Clinical Trial.
The metabolic footprint of aging in mice.
Houtkooper RH, Argmann C, Houten SM, Cantó C, Jeninga EH, Andreux PA, Thomas C, Doenlen R, Schoonjans K, Auwerx J. Houtkooper RH, et al. Among authors: andreux pa. Sci Rep. 2011;1:134. doi: 10.1038/srep00134. Epub 2011 Oct 31. Sci Rep. 2011. PMID: 22355651 Free PMC article.
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Among authors: andreux pa. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
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