Andrade-Gordon P - Search Results

1

Aza-bicyclic amino acid sulfonamides as alpha(4)beta(1)/alpha(4)beta(7) integrin antagonists.

Dyatkin AB, Hoekstra WJ, Kinney WA, Kontoyianni M, Santulli RJ, Kimball ES, Fisher MC, Prouty SM, Abraham WM, de Garavilla L, Andrade-Gordon P, Hlasta DJ, He W, Hornby PJ, Damiano BP, Maryanoff BE. Dyatkin AB, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):591-6. doi: 10.1016/j.bmcl.2003.11.063. Bioorg Med Chem Lett. 2004. PMID: 14741249

2

Discovery of potent peptide-mimetic antagonists for the human thrombin receptor, protease-activated receptor-1 (PAR-1).

Maryanoff BE, Zhang HC, Andrade-Gordon P, Derian CK. Maryanoff BE, et al. Curr Med Chem Cardiovasc Hematol Agents. 2003 Mar;1(1):13-36. doi: 10.2174/1568016033356724. Curr Med Chem Cardiovasc Hematol Agents. 2003. PMID: 15317288 Review.

3

Synthesis and biological evaluation of novel pyridazinone-based alpha4 integrin receptor antagonists.

Gong Y, Barbay JK, Dyatkin AB, Miskowski TA, Kimball ES, Prouty SM, Fisher MC, Santulli RJ, Schneider CR, Wallace NH, Ballentine SA, Hageman WE, Masucci JA, Maryanoff BE, Damiano BP, Andrade-Gordon P, Hlasta DJ, Hornby PJ, He W. Gong Y, et al. J Med Chem. 2006 Jun 1;49(11):3402-11. doi: 10.1021/jm060031q. J Med Chem. 2006. PMID: 16722660

4

Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists.

Matthews JM, Greco MN, Hecker LR, Hoekstra WJ, Andrade-Gordon P, de Garavilla L, Demarest KT, Ericson E, Gunnet JW, Hageman W, Look R, Moore JB, Maryanoff BE. Matthews JM, et al. Bioorg Med Chem Lett. 2003 Feb 24;13(4):753-6. doi: 10.1016/s0960-894x(02)01059-4. Bioorg Med Chem Lett. 2003. PMID: 12639574

5

Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.

Costanzo MJ, Yabut SC, Almond HR Jr, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, Maryanoff BE. Costanzo MJ, et al. J Med Chem. 2003 Aug 28;46(18):3865-76. doi: 10.1021/jm030050p. J Med Chem. 2003. PMID: 12930148

6

Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates.

Matthews JM, Hoekstra WJ, Dyatkin AB, Hecker LR, Hlasta DJ, Poulter BL, Andrade-Gordon P, de Garavilla L, Demarest KT, Ericson E, Gunnet JW, Hageman W, Look R, Moore JB, Reynolds CH, Maryanoff BE. Matthews JM, et al. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2747-52. doi: 10.1016/j.bmcl.2004.03.083. Bioorg Med Chem Lett. 2004. PMID: 15125926

7

Bridged bicyclic vasopressin receptor antagonists with V(2)-selective or dual V(1a)/V(2) activity.

Dyatkin AB, Hoekstra WJ, Hlasta DJ, Andrade-Gordon P, de Garavilla L, Demarest KT, Gunnet JW, Hageman W, Look R, Maryanoff BE. Dyatkin AB, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3081-4. doi: 10.1016/s0960-894x(02)00649-2. Bioorg Med Chem Lett. 2002. PMID: 12372506

8

Thrombin receptor (PAR-1) antagonists. Heterocycle-based peptidomimetics of the SFLLR agonist motif.

Hoekstra WJ, Hulshizer BL, McComsey DF, Andrade-Gordon P, Kauffman JA, Addo MF, Oksenberg D, Scarborough RM, Maryanoff BE. Hoekstra WJ, et al. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1649-54. doi: 10.1016/s0960-894x(98)00292-3. Bioorg Med Chem Lett. 1998. PMID: 9873407

9

1,2,4-triazolo[3,4-a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists.

Lawson EC, Hoekstra WJ, Addo MF, Andrade-Gordon P, Damiano BP, Kauffman JA, Mitchell JA, Maryanoff BE. Lawson EC, et al. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2619-22. doi: 10.1016/s0960-894x(01)00529-7. Bioorg Med Chem Lett. 2001. PMID: 11551763

10

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.

Zhang HC, Ye H, Conway BR, Derian CK, Addo MF, Kuo GH, Hecker LR, Croll DR, Li J, Westover L, Xu JZ, Look R, Demarest KT, Andrade-Gordon P, Damiano BP, Maryanoff BE. Zhang HC, et al. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3245-50. doi: 10.1016/j.bmcl.2004.03.090. Bioorg Med Chem Lett. 2004. PMID: 15149684

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