Andersson TB - Search Results

1

Evolution of Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.

Andersson TB. Andersson TB. Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):234-238. doi: 10.1111/bcpt.12804. Epub 2017 Jul 3. Basic Clin Pharmacol Toxicol. 2017. PMID: 28470941 Free article. Review.

2

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.

Lauschke VM, Hendriks DF, Bell CC, Andersson TB, Ingelman-Sundberg M. Lauschke VM, et al. Among authors: andersson tb. Chem Res Toxicol. 2016 Dec 19;29(12):1936-1955. doi: 10.1021/acs.chemrestox.6b00150. Epub 2016 Sep 23. Chem Res Toxicol. 2016. PMID: 27661221 Review.

3

Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.

Bell CC, Lauschke VM, Vorrink SU, Palmgren H, Duffin R, Andersson TB, Ingelman-Sundberg M. Bell CC, et al. Among authors: andersson tb. Drug Metab Dispos. 2017 Apr;45(4):419-429. doi: 10.1124/dmd.116.074369. Epub 2017 Jan 30. Drug Metab Dispos. 2017. PMID: 28137721 Free PMC article.

4

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.

Hendriks DFG, Vorrink SU, Smutny T, Sim SC, Nordling Å, Ullah S, Kumondai M, Jones BC, Johansson I, Andersson TB, Lauschke VM, Ingelman-Sundberg M. Hendriks DFG, et al. Among authors: andersson tb. Clin Pharmacol Ther. 2020 Oct;108(4):844-855. doi: 10.1002/cpt.1860. Epub 2020 May 22. Clin Pharmacol Ther. 2020. PMID: 32320483

5

Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes.

Sjogren AK, Liljevald M, Glinghammar B, Sagemark J, Li XQ, Jonebring A, Cotgreave I, Brolén G, Andersson TB. Sjogren AK, et al. Among authors: andersson tb. Arch Toxicol. 2014 Jul;88(7):1427-37. doi: 10.1007/s00204-014-1265-z. Epub 2014 Jun 10. Arch Toxicol. 2014. PMID: 24912781

6

Drug-induced liver injury in humans: the case of ximelagatran.

Keisu M, Andersson TB. Keisu M, et al. Among authors: andersson tb. Handb Exp Pharmacol. 2010;(196):407-18. doi: 10.1007/978-3-642-00663-0_13. Handb Exp Pharmacol. 2010. PMID: 20020269 Review.

7

The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human.

Andersson TB, Kanebratt KP, Kenna JG. Andersson TB, et al. Expert Opin Drug Metab Toxicol. 2012 Jul;8(7):909-20. doi: 10.1517/17425255.2012.685159. Epub 2012 May 8. Expert Opin Drug Metab Toxicol. 2012. PMID: 22568886 Review.

8

Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model.

Bauer S, Wennberg Huldt C, Kanebratt KP, Durieux I, Gunne D, Andersson S, Ewart L, Haynes WG, Maschmeyer I, Winter A, Ämmälä C, Marx U, Andersson TB. Bauer S, et al. Among authors: andersson s, andersson tb. Sci Rep. 2017 Nov 6;7(1):14620. doi: 10.1038/s41598-017-14815-w. Sci Rep. 2017. PMID: 29097671 Free PMC article.

9

In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system.

Darnell M, Ulvestad M, Ellis E, Weidolf L, Andersson TB. Darnell M, et al. Among authors: andersson tb. J Pharmacol Exp Ther. 2012 Oct;343(1):134-44. doi: 10.1124/jpet.112.195834. Epub 2012 Jul 9. J Pharmacol Exp Ther. 2012. PMID: 22776955

10

Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition.

Deharde D, Schneider C, Hiller T, Fischer N, Kegel V, Lübberstedt M, Freyer N, Hengstler JG, Andersson TB, Seehofer D, Pratschke J, Zeilinger K, Damm G. Deharde D, et al. Among authors: andersson tb. Arch Toxicol. 2016 Oct;90(10):2497-511. doi: 10.1007/s00204-016-1758-z. Epub 2016 Jun 21. Arch Toxicol. 2016. PMID: 27325308

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