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Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Basile G, Vetere A, Hu J, Ijaduola O, Zhang Y, Liu KC, Eltony AM, De Jesus DF, Fukuda K, Doherty G, Leech CA, Chepurny OG, Holz GG, Yun SH, Andersson O, Choudhary A, Wagner BK, Kulkarni RN. Basile G, et al. Among authors: andersson o. Cell Metab. 2023 Jul 11;35(7):1242-1260.e9. doi: 10.1016/j.cmet.2023.05.007. Epub 2023 Jun 19. Cell Metab. 2023. PMID: 37339634 Free PMC article.
SerpinB1 Promotes Pancreatic β Cell Proliferation.
El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. El Ouaamari A, et al. Among authors: andersson o. Cell Metab. 2016 Jan 12;23(1):194-205. doi: 10.1016/j.cmet.2015.12.001. Epub 2015 Dec 15. Cell Metab. 2016. PMID: 26701651 Free PMC article.
Critical role for adenosine receptor A2a in β-cell proliferation.
Schulz N, Liu KC, Charbord J, Mattsson CL, Tao L, Tworus D, Andersson O. Schulz N, et al. Among authors: andersson o. Mol Metab. 2016 Sep 20;5(11):1138-1146. doi: 10.1016/j.molmet.2016.09.006. eCollection 2016 Nov. Mol Metab. 2016. PMID: 27818940 Free PMC article.
Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors.
Liu KC, Leuckx G, Sakano D, Seymour PA, Mattsson CL, Rautio L, Staels W, Verdonck Y, Serup P, Kume S, Heimberg H, Andersson O. Liu KC, et al. Among authors: andersson o. Diabetes. 2018 Jan;67(1):58-70. doi: 10.2337/db16-1587. Epub 2017 Oct 6. Diabetes. 2018. PMID: 28986398 Free PMC article.
In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.
Chu L, Terasaki M, Mattsson CL, Teinturier R, Charbord J, Dirice E, Liu KC, Miskelly MG, Zhou Q, Wierup N, Kulkarni RN, Andersson O. Chu L, et al. Among authors: andersson o. Cell Chem Biol. 2022 Sep 15;29(9):1368-1380.e5. doi: 10.1016/j.chembiol.2022.08.001. Epub 2022 Aug 22. Cell Chem Biol. 2022. PMID: 35998625 Free PMC article.
Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function.
Bertolino P, Holmberg R, Reissmann E, Andersson O, Berggren PO, Ibáñez CF. Bertolino P, et al. Among authors: andersson o. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7246-51. doi: 10.1073/pnas.0801285105. Epub 2008 May 14. Proc Natl Acad Sci U S A. 2008. PMID: 18480258 Free PMC article.
405 results