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CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function-Structure Characterization of T-Cell Engaging Bispecific Antibody Proteoforms and Product-Related Variants.
Lippold S, Hook M, Spick C, Knaupp A, Whang K, Ruperti F, Cadang L, Andersen N, Vogt A, Grote M, Reusch D, Haberger M, Yang F, Schlothauer T. Lippold S, et al. Among authors: andersen n. Anal Chem. 2023 Jan 31;95(4):2260-2268. doi: 10.1021/acs.analchem.2c03827. Epub 2023 Jan 13. Anal Chem. 2023. PMID: 36638115
From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies.
Goyon A, Dai L, Chen T, Wei B, Yang F, Andersen N, Kopf R, Leiss M, Mølhøj M, Guillarme D, Stella C. Goyon A, et al. Among authors: andersen n. J Chromatogr A. 2020 Mar 29;1615:460740. doi: 10.1016/j.chroma.2019.460740. Epub 2019 Nov 27. J Chromatogr A. 2020. PMID: 31796250
Discovery of a dual pathway aggregation mechanism for a therapeutic constrained peptide.
Chen T, Tang S, Hecht ES, Yen CW, Andersen N, Chin S, Cadang L, Roper B, Estevez A, Rohou A, Chang D, Dai L, Liu P, Al-Sayah M, Nagapudi K, Lin F, Famili A, Hu C, Kuhn R, Stella C, Crittenden CM, Gruenhagen JA, Venkatramani C, Hannoush RN, Leung D, Vandlen R, Yehl P. Chen T, et al. Among authors: andersen n. J Pharm Sci. 2021 Jun;110(6):2362-2371. doi: 10.1016/j.xphs.2020.12.041. Epub 2021 Feb 27. J Pharm Sci. 2021. PMID: 33652014
Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics.
Chu PY, Wang H, Ross E, Stephens N, Zhang HM, Andersen N, Chan W, Shivva V, Crowell SR, Spiess C, Holder PG, Agard NJ, Ji C, Chen J, Sreedhara A, Wang J, Wu C, Liu Y, Tran JC. Chu PY, et al. Among authors: andersen n. Anal Chem. 2023 Dec 12;95(49):17957-17961. doi: 10.1021/acs.analchem.3c02133. Epub 2023 Nov 30. Anal Chem. 2023. PMID: 38084380
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, van Lookeren Campagne M, Rajagopal K, Dickmann L, Scheer JM, Kelley RF. Tesar D, et al. Among authors: andersen n. MAbs. 2017 Nov/Dec;9(8):1297-1305. doi: 10.1080/19420862.2017.1372078. Epub 2017 Aug 30. MAbs. 2017. PMID: 28854082 Free PMC article.
Presence and development of diabetic retinopathy in 16 999 patients with type 1 diabetes in the Danish Registry of Diabetic Retinopathy.
Stokholm L, Pedersen FN, Andersen N, Andresen J, Bek T, Dinesen S, Hajari J, Heegaard S, Højlund K, Laugesen CS, Kawasaki R, Möller S, Schielke KC, Subhi Y, Thykjær AS, Grauslund J. Stokholm L, et al. Among authors: andersen n. Acta Ophthalmol. 2024 May 18. doi: 10.1111/aos.16707. Online ahead of print. Acta Ophthalmol. 2024. PMID: 38761021
1,188 results