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Generation and Characterization of Iduronidase-Cleavable ADCs.
Jäger S, Könning D, Rasche N, Hart F, Sensbach J, Krug C, Raab-Westphal S, Richter K, Unverzagt C, Hecht S, Anderl J, Schröter C. Jäger S, et al. Among authors: anderl j. Bioconjug Chem. 2023 Dec 20;34(12):2221-2233. doi: 10.1021/acs.bioconjchem.3c00363. Epub 2023 Dec 6. Bioconjug Chem. 2023. PMID: 38054705
Signal peptide mimicry primes Sec61 for client-selective inhibition.
Rehan S, Tranter D, Sharp PP, Craven GB, Lowe E, Anderl JL, Muchamuel T, Abrishami V, Kuivanen S, Wenzell NA, Jennings A, Kalyanaraman C, Strandin T, Javanainen M, Vapalahti O, Jacobson MP, McMinn D, Kirk CJ, Huiskonen JT, Taunton J, Paavilainen VO. Rehan S, et al. Among authors: anderl jl. Nat Chem Biol. 2023 Sep;19(9):1054-1062. doi: 10.1038/s41589-023-01326-1. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169961 Free PMC article.
Antibody-drug conjugates: What drives their progress?
Pander G, Uhl P, Kühl N, Haberkorn U, Anderl J, Mier W. Pander G, et al. Among authors: anderl j. Drug Discov Today. 2022 Oct;27(10):103311. doi: 10.1016/j.drudis.2022.06.011. Epub 2022 Jul 3. Drug Discov Today. 2022. PMID: 35787480 Review.
Author Correction: TP53 loss creates therapeutic vulnerability in colorectal cancer.
Liu Y, Zhang X, Han C, Wan G, Huang X, Ivan C, Jiang D, Rodriguez-Aguayo C, Lopez-Berestein G, Rao PH, Maru DM, Pahl A, He X, Sood AK, Ellis LM, Anderl J, Lu X. Liu Y, et al. Among authors: anderl j. Nature. 2021 Sep;597(7875):E6. doi: 10.1038/s41586-021-03664-3. Nature. 2021. PMID: 34433970 No abstract available.
Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases.
Dickgiesser S, Rieker M, Mueller-Pompalla D, Schröter C, Tonillo J, Warszawski S, Raab-Westphal S, Kühn S, Knehans T, Könning D, Dotterweich J, Betz UAK, Anderl J, Hecht S, Rasche N. Dickgiesser S, et al. Among authors: anderl j. Bioconjug Chem. 2020 Apr 15;31(4):1070-1076. doi: 10.1021/acs.bioconjchem.0c00061. Epub 2020 Mar 12. Bioconjug Chem. 2020. PMID: 32134638
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S,3 R)- N-(( S)-3-(Cyclopent-1-en-1-yl)-1-(( R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-(( S)-2-(2-morpholinoacetamido)propanamido)propenamide).
Johnson HWB, Lowe E, Anderl JL, Fan A, Muchamuel T, Bowers S, Moebius DC, Kirk C, McMinn DL. Johnson HWB, et al. Among authors: anderl jl. J Med Chem. 2018 Dec 27;61(24):11127-11143. doi: 10.1021/acs.jmedchem.8b01201. Epub 2018 Dec 11. J Med Chem. 2018. PMID: 30380863
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