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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Among authors: anandasabapathy n. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N. Nirschl CJ, et al. Among authors: anandasabapathy n. Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016. Cell. 2017. PMID: 28666115 Free PMC article.
The role of dendritic cells in cancer and anti-tumor immunity.
Marciscano AE, Anandasabapathy N. Marciscano AE, et al. Among authors: anandasabapathy n. Semin Immunol. 2021 Feb;52:101481. doi: 10.1016/j.smim.2021.101481. Epub 2021 May 20. Semin Immunol. 2021. PMID: 34023170 Free PMC article. Review.
Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages.
Valencia JC, Erwin-Cohen RA, Clavijo PE, Allen C, Sanford ME, Day CP, Hess MM, Johnson M, Yin J, Fenimore JM, Bettencourt IA, Tsuneyama K, Romero ME, Klarmann KD, Jiang P, Bae HR, McVicar DW, Merlino G, Edmondson EF, Anandasabapathy N, Young HA. Valencia JC, et al. Among authors: anandasabapathy n. Cancer Res. 2021 Dec 1;81(23):5977-5990. doi: 10.1158/0008-5472.CAN-21-1148. Epub 2021 Oct 12. Cancer Res. 2021. PMID: 34642183 Free PMC article.
An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes.
Jaiswal A, Verma A, Dannenfelser R, Melssen M, Tirosh I, Izar B, Kim TG, Nirschl CJ, Devi KSP, Olson WC Jr, Slingluff CL Jr, Engelhard VH, Garraway L, Regev A, Minkis K, Yoon CH, Troyanskaya O, Elemento O, Suárez-Fariñas M, Anandasabapathy N. Jaiswal A, et al. Among authors: anandasabapathy n. Cancer Cell. 2022 May 9;40(5):524-544.e5. doi: 10.1016/j.ccell.2022.04.005. Epub 2022 May 9. Cancer Cell. 2022. PMID: 35537413 Free PMC article.
Immune Checkpoint Blockade and Skin Toxicity Pathogenesis.
Ma B, Anandasabapathy N. Ma B, et al. Among authors: anandasabapathy n. J Invest Dermatol. 2022 Mar;142(3 Pt B):951-959. doi: 10.1016/j.jid.2021.06.040. Epub 2021 Nov 26. J Invest Dermatol. 2022. PMID: 34844731 Free article. Review.
T cell egress via lymphatic vessels is tuned by antigen encounter and limits tumor control.
Steele MM, Jaiswal A, Delclaux I, Dryg ID, Murugan D, Femel J, Son S, du Bois H, Hill C, Leachman SA, Chang YH, Coussens LM, Anandasabapathy N, Lund AW. Steele MM, et al. Among authors: anandasabapathy n. Nat Immunol. 2023 Apr;24(4):664-675. doi: 10.1038/s41590-023-01443-y. Epub 2023 Feb 27. Nat Immunol. 2023. PMID: 36849745 Free PMC article.
40 results