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AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination.
Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, Schaeffer EM, Lotan TL, Isaacs WB, Netto GJ, De Marzo AM, Nelson WG, An SS, Yegnasubramanian S. Haffner MC, et al. Among authors: an ss. Nat Commun. 2017 Jul 26;8(1):142. doi: 10.1038/s41467-017-00084-8. Nat Commun. 2017. PMID: 28747635 Free PMC article.
PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2.
Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C. Murphy SA, et al. Among authors: an ss. Nat Commun. 2021 Mar 12;12(1):1648. doi: 10.1038/s41467-021-21957-z. Nat Commun. 2021. PMID: 33712605 Free PMC article.
Cell stiffness, contractile stress and the role of extracellular matrix.
An SS, Kim J, Ahn K, Trepat X, Drake KJ, Kumar S, Ling G, Purington C, Rangasamy T, Kensler TW, Mitzner W, Fredberg JJ, Biswal S. An SS, et al. Biochem Biophys Res Commun. 2009 May 15;382(4):697-703. doi: 10.1016/j.bbrc.2009.03.118. Epub 2009 Mar 25. Biochem Biophys Res Commun. 2009. PMID: 19327344 Free PMC article.
LAMC2 enhances the metastatic potential of lung adenocarcinoma.
Moon YW, Rao G, Kim JJ, Shim HS, Park KS, An SS, Kim B, Steeg PS, Sarfaraz S, Changwoo Lee L, Voeller D, Choi EY, Luo J, Palmieri D, Chung HC, Kim JH, Wang Y, Giaccone G. Moon YW, et al. Among authors: an ss. Cell Death Differ. 2015 Aug;22(8):1341-52. doi: 10.1038/cdd.2014.228. Epub 2015 Jan 16. Cell Death Differ. 2015. PMID: 25591736 Free PMC article.
Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression.
Hurley PJ, Hughes RM, Simons BW, Huang J, Miller RM, Shinder B, Haffner MC, Esopi D, Kimura Y, Jabbari J, Ross AE, Erho N, Vergara IA, Faraj SF, Davicioni E, Netto GJ, Yegnasubramanian S, An SS, Schaeffer EM. Hurley PJ, et al. Among authors: an ss. Cancer Res. 2015 Oct 15;75(20):4322-34. doi: 10.1158/0008-5472.CAN-15-0024. Epub 2015 Aug 20. Cancer Res. 2015. PMID: 26294211 Free PMC article.
Mechanistically, we demonstrate that SPARCL1 expression is directly suppressed by androgen-induced AR activation and binding at the SPARCL1 locus via an epigenetic mechanism, and these events can be pharmacologically attenuated with either AR antagonists or HDAC inhibitors …
Mechanistically, we demonstrate that SPARCL1 expression is directly suppressed by androgen-induced AR activation and binding at the SPARCL1 …
4,025 results