TRIAD1 Is a Novel Transcriptional Target of p53 and Regulates Nutlin-3a-Induced Cell Death.
Lee J, An S, Choi YM, Jung JH, Li L, Meng H, Dong Y, Ahn KJ, An IS, Bae S.
Lee J, et al. Among authors: an is, an s.
J Cell Biochem. 2017 Jul;118(7):1733-1740. doi: 10.1002/jcb.25831. Epub 2017 Jan 10.
J Cell Biochem. 2017.
PMID: 27935098
Nutlin-3a is a non-genotoxic, p53-activating, MDM2 inhibitor being investigated as an anticancer agent. ...Using in silico analysis and promoter luciferase assays, we demonstrated that p53-mediated transcription of TRIAD1 is mediated by a p53 consensus sequen …
Nutlin-3a is a non-genotoxic, p53-activating, MDM2 inhibitor being investigated as an anticancer agent. ...Using in silico ana …