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IQGAP1 promotes mitochondrial damage and activation of the mtDNA sensor cGAS-STING pathway to induce endothelial cell pyroptosis leading to atherosclerosis.
An C, Sun F, Liu C, Huang S, Xu T, Zhang C, Ge S. An C, et al. Int Immunopharmacol. 2023 Oct;123:110795. doi: 10.1016/j.intimp.2023.110795. Epub 2023 Aug 17. Int Immunopharmacol. 2023. PMID: 37597406
Atherosclerosis (AS) is the most common cardiovascular disease and has limited therapeutic options. IQ motif-containing GTPase-activating protein 1 (IQGAP1) is an important scaffolding protein regulating mitochondrial function influencing endothelial cell activity. ...Furt …
Atherosclerosis (AS) is the most common cardiovascular disease and has limited therapeutic options. IQ motif-containing GTPase-activating pr …
Dihydrostilbenes and flavonoids from whole plants of Jacobaea vulgaris.
Lee S, Son MG, Kim YM, An CY, Kim HJ, Nhoek P, Pel P, Won H, Lee Y, Yun N, Paik JH, Bazarragchaa B, Kim HW, Choi YH, Oh WK, Lee CH, Chin YW. Lee S, et al. Among authors: an cy. Phytochemistry. 2024 Jun;222:114107. doi: 10.1016/j.phytochem.2024.114107. Epub 2024 Apr 23. Phytochemistry. 2024. PMID: 38663823
1,561 results