Amrein L - Search Results

1

A phase I study of imatinib mesylate in combination with chlorambucil in previously treated chronic lymphocytic leukemia patients.

Hebb J, Assouline S, Rousseau C, Desjardins P, Caplan S, Egorin MJ, Amrein L, Aloyz R, Panasci L. Hebb J, et al. Among authors: amrein l. Cancer Chemother Pharmacol. 2011 Sep;68(3):643-51. doi: 10.1007/s00280-010-1530-7. Epub 2010 Dec 1. Cancer Chemother Pharmacol. 2011. PMID: 21120481 Clinical Trial.

2

Dasatinib sensitizes primary chronic lymphocytic leukaemia lymphocytes to chlorambucil and fludarabine in vitro.

Amrein L, Hernandez TA, Ferrario C, Johnston J, Gibson SB, Panasci L, Aloyz R. Amrein L, et al. Br J Haematol. 2008 Dec;143(5):698-706. doi: 10.1111/j.1365-2141.2008.07418.x. Br J Haematol. 2008. PMID: 19062342 Free article.

3

Dual inhibition of the homologous recombinational repair and the nonhomologous end-joining repair pathways in chronic lymphocytic leukemia therapy.

Amrein L, Davidson D, Shawi M, Petruccelli LA, Miller WH Jr, Aloyz R, Panasci L. Amrein L, et al. Leuk Res. 2011 Aug;35(8):1080-6. doi: 10.1016/j.leukres.2011.01.004. Epub 2011 Feb 1. Leuk Res. 2011. PMID: 21281966

4

The phosphatidylinositol-3 kinase I inhibitor BKM120 induces cell death in B-chronic lymphocytic leukemia cells in vitro.

Amrein L, Shawi M, Grenier J, Aloyz R, Panasci L. Amrein L, et al. Int J Cancer. 2013 Jul;133(1):247-52. doi: 10.1002/ijc.27989. Epub 2013 Jan 15. Int J Cancer. 2013. PMID: 23238639 Free PMC article.

5

IND.216: a phase II study of buparlisib and associated biomarkers, raptor and p70S6K, in patients with relapsed and refractory chronic lymphocytic leukemia.

Assouline S, Amrein L, Aloyz R, Banerji V, Caplan S, Owen C, Hasegawa W, Robinson S, Shivakumar S, Prica A, Peters A, Hagerman L, Rodriguez L, Skamene T, Panasci L, Chen BE, Hay AE. Assouline S, et al. Among authors: amrein l. Leuk Lymphoma. 2020 Jul;61(7):1653-1659. doi: 10.1080/10428194.2020.1734594. Epub 2020 Mar 10. Leuk Lymphoma. 2020. PMID: 32154751 Clinical Trial.

6

Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase.

Amrein L, Loignon M, Goulet AC, Dunn M, Jean-Claude B, Aloyz R, Panasci L. Amrein L, et al. J Pharmacol Exp Ther. 2007 Jun;321(3):848-55. doi: 10.1124/jpet.106.118356. Epub 2007 Mar 9. J Pharmacol Exp Ther. 2007. PMID: 17351105

7

p53 and autophagy contribute to dasatinib resistance in primary CLL lymphocytes.

Amrein L, Soulières D, Johnston JB, Aloyz R. Amrein L, et al. Leuk Res. 2011 Jan;35(1):99-102. doi: 10.1016/j.leukres.2010.05.029. Epub 2010 Jun 22. Leuk Res. 2011. PMID: 20573397

8

Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond.

Davidson D, Amrein L, Panasci L, Aloyz R. Davidson D, et al. Among authors: amrein l. Front Pharmacol. 2013 Jan 31;4:5. doi: 10.3389/fphar.2013.00005. eCollection 2013. Front Pharmacol. 2013. PMID: 23386830 Free PMC article.

9

Simultaneous inhibition of ATR and PARP sensitizes colon cancer cell lines to irinotecan.

Abu-Sanad A, Wang Y, Hasheminasab F, Panasci J, Noë A, Rosca L, Davidson D, Amrein L, Sharif-Askari B, Aloyz R, Panasci L. Abu-Sanad A, et al. Among authors: amrein l. Front Pharmacol. 2015 Jul 22;6:147. doi: 10.3389/fphar.2015.00147. eCollection 2015. Front Pharmacol. 2015. PMID: 26257651 Free PMC article.

10

Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells.

Davidson D, Coulombe Y, Martinez-Marignac VL, Amrein L, Grenier J, Hodkinson K, Masson JY, Aloyz R, Panasci L. Davidson D, et al. Among authors: amrein l. Invest New Drugs. 2012 Jun;30(3):1248-56. doi: 10.1007/s10637-010-9626-9. Epub 2011 Jan 11. Invest New Drugs. 2012. PMID: 21221710

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