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Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes.
JCI Insight. 2021 Jan 11;6(1):e143791. doi: 10.1172/jci.insight.143791.
JCI Insight. 2021.
PMID: 33427207
Free PMC article.
Interorgan Crosstalk Contributing to β-Cell Dysfunction.
Tanabe K, Amo-Shiinoki K, Hatanaka M, Tanizawa Y.
Tanabe K, et al. Among authors: amo shiinoki k.
J Diabetes Res. 2017;2017:3605178. doi: 10.1155/2017/3605178. Epub 2017 Jan 12.
J Diabetes Res. 2017.
PMID: 28168202
Free PMC article.
Review.
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Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.
Kondo M, Tanabe K, Amo-Shiinoki K, Hatanaka M, Morii T, Takahashi H, Seino S, Yamada Y, Tanizawa Y.
Kondo M, et al. Among authors: amo shiinoki k.
Diabetologia. 2018 Oct;61(10):2189-2201. doi: 10.1007/s00125-018-4679-y. Epub 2018 Jul 28.
Diabetologia. 2018.
PMID: 30054673
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Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes.
Fukuda T, Bouchi R, Takeuchi T, Amo-Shiinoki K, Kudo A, Tanaka S, Tanabe M, Akashi T, Hirayama K, Odamaki T, Igarashi M, Kimura I, Tanabe K, Tanizawa Y, Yamada T, Ogawa Y.
Fukuda T, et al. Among authors: amo shiinoki k.
Diabetes Care. 2021 Apr;44(4):1002-1011. doi: 10.2337/dc20-0864. Epub 2021 Feb 24.
Diabetes Care. 2021.
PMID: 33627367
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Gsk-3-Mediated Proteasomal Degradation of ATF4 Is a Proapoptotic Mechanism in Mouse Pancreatic β-Cells.
Nagao Y, Amo-Shiinoki K, Nakabayashi H, Hatanaka M, Kondo M, Matsunaga K, Emoto M, Okuya S, Tanizawa Y, Tanabe K.
Nagao Y, et al. Among authors: amo shiinoki k.
Int J Mol Sci. 2022 Nov 5;23(21):13586. doi: 10.3390/ijms232113586.
Int J Mol Sci. 2022.
PMID: 36362372
Free PMC article.
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Hachimijiogan, a traditional herbal medicine, modulates adipose cell function and ameliorates diet-induced obesity and insulin resistance in mice.
Kagawa S, Tanabe K, Hiromura M, Ogawa K, Koga T, Maeda T, Amo-Shiinoki K, Ochi H, Ichiki Y, Fukuyama S, Suzuki S, Suizu N, Ohmine T, Hamachi S, Tsuneki H, Okuya S, Sasaoka T, Tanizawa Y, Nagashima F.
Kagawa S, et al. Among authors: amo shiinoki k.
Front Pharmacol. 2023 May 12;14:1167934. doi: 10.3389/fphar.2023.1167934. eCollection 2023.
Front Pharmacol. 2023.
PMID: 37251332
Free PMC article.
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Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling.
Yuasa T, Amo-Shiinoki K, Ishikura S, Takahara M, Matsuoka T, Kaneto H, Kuroda A, Matsuhisa M, Hashida S.
Yuasa T, et al. Among authors: amo shiinoki k.
Diabetologia. 2016 Dec;59(12):2711-2721. doi: 10.1007/s00125-016-4102-5. Epub 2016 Sep 30.
Diabetologia. 2016.
PMID: 27695899
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