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Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes.
Amo-Shiinoki K, Tanabe K, Hoshii Y, Matsui H, Harano R, Fukuda T, Takeuchi T, Bouchi R, Takagi T, Hatanaka M, Takeda K, Okuya S, Nishimura W, Kudo A, Tanaka S, Tanabe M, Akashi T, Yamada T, Ogawa Y, Ikeda E, Nagano H, Tanizawa Y. Amo-Shiinoki K, et al. JCI Insight. 2021 Jan 11;6(1):e143791. doi: 10.1172/jci.insight.143791. JCI Insight. 2021. PMID: 33427207 Free PMC article.
Interorgan Crosstalk Contributing to β-Cell Dysfunction.
Tanabe K, Amo-Shiinoki K, Hatanaka M, Tanizawa Y. Tanabe K, et al. Among authors: amo shiinoki k. J Diabetes Res. 2017;2017:3605178. doi: 10.1155/2017/3605178. Epub 2017 Jan 12. J Diabetes Res. 2017. PMID: 28168202 Free PMC article. Review.
Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes.
Fukuda T, Bouchi R, Takeuchi T, Amo-Shiinoki K, Kudo A, Tanaka S, Tanabe M, Akashi T, Hirayama K, Odamaki T, Igarashi M, Kimura I, Tanabe K, Tanizawa Y, Yamada T, Ogawa Y. Fukuda T, et al. Among authors: amo shiinoki k. Diabetes Care. 2021 Apr;44(4):1002-1011. doi: 10.2337/dc20-0864. Epub 2021 Feb 24. Diabetes Care. 2021. PMID: 33627367
Hachimijiogan, a traditional herbal medicine, modulates adipose cell function and ameliorates diet-induced obesity and insulin resistance in mice.
Kagawa S, Tanabe K, Hiromura M, Ogawa K, Koga T, Maeda T, Amo-Shiinoki K, Ochi H, Ichiki Y, Fukuyama S, Suzuki S, Suizu N, Ohmine T, Hamachi S, Tsuneki H, Okuya S, Sasaoka T, Tanizawa Y, Nagashima F. Kagawa S, et al. Among authors: amo shiinoki k. Front Pharmacol. 2023 May 12;14:1167934. doi: 10.3389/fphar.2023.1167934. eCollection 2023. Front Pharmacol. 2023. PMID: 37251332 Free PMC article.