Ammirati MJ - Search Results

1

cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.

Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, McClure LD, McPherson RK, Orena SJ, Parker JC, Polivkova J, Qiu X, Soeller WC, Soglia CB, Treadway JL, VanVolkenburg MA, Wang H, Wilder DC, Olson TV. Wright SW, et al. Among authors: ammirati mj. J Med Chem. 2006 Jun 1;49(11):3068-76. doi: 10.1021/jm0600085. J Med Chem. 2006. PMID: 16722626

2

Simple procedure for recovery of crystallizable human recombinant renin from mammalian cell-conditioned medium.

Geoghegan KF, Lanzetti AJ, Ammirati MJ, Danley DE, O'Connor BA, Hobart PM. Geoghegan KF, et al. Among authors: ammirati mj. Adv Exp Med Biol. 1991;306:379-81. doi: 10.1007/978-1-4684-6012-4_48. Adv Exp Med Biol. 1991. PMID: 1812731 No abstract available.

3

Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coli.

Danley DE, Geoghegan KF, Scheld KG, Lee SE, Merson JR, Hawrylik SJ, Rickett GA, Ammirati MJ, Hobart PM. Danley DE, et al. Among authors: ammirati mj. Biochem Biophys Res Commun. 1989 Dec 29;165(3):1043-50. doi: 10.1016/0006-291x(89)92707-1. Biochem Biophys Res Commun. 1989. PMID: 2692557

4

Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

Rath VL, Ammirati M, LeMotte PK, Fennell KF, Mansour MN, Danley DE, Hynes TR, Schulte GK, Wasilko DJ, Pandit J. Rath VL, et al. Mol Cell. 2000 Jul;6(1):139-48. Mol Cell. 2000. PMID: 10949035 Free article.

5

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ. Rath VL, et al. Chem Biol. 2000 Sep;7(9):677-82. doi: 10.1016/s1074-5521(00)00004-1. Chem Biol. 2000. PMID: 10980448

6

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.

Dow RL, Schneider SR, Paight ES, Hank RF, Chiang P, Cornelius P, Lee E, Newsome WP, Swick AG, Spitzer J, Hargrove DM, Patterson TA, Pandit J, Chrunyk BA, LeMotte PK, Danley DE, Rosner MH, Ammirati MJ, Simons SP, Schulte GK, Tate BF, DaSilva-Jardine P. Dow RL, et al. Among authors: ammirati mj. Bioorg Med Chem Lett. 2003 Feb 10;13(3):379-82. doi: 10.1016/s0960-894x(02)00947-2. Bioorg Med Chem Lett. 2003. PMID: 12565933

7

Specificity determinants of human cathepsin s revealed by crystal structures of complexes.

Pauly TA, Sulea T, Ammirati M, Sivaraman J, Danley DE, Griffor MC, Kamath AV, Wang IK, Laird ER, Seddon AP, Ménard R, Cygler M, Rath VL. Pauly TA, et al. Biochemistry. 2003 Mar 25;42(11):3203-13. doi: 10.1021/bi027308i. Biochemistry. 2003. PMID: 12641451

8

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.

Qiu X, Mistry A, Ammirati MJ, Chrunyk BA, Clark RW, Cong Y, Culp JS, Danley DE, Freeman TB, Geoghegan KF, Griffor MC, Hawrylik SJ, Hayward CM, Hensley P, Hoth LR, Karam GA, Lira ME, Lloyd DB, McGrath KM, Stutzman-Engwall KJ, Subashi AK, Subashi TA, Thompson JF, Wang IK, Zhao H, Seddon AP. Qiu X, et al. Among authors: ammirati mj. Nat Struct Mol Biol. 2007 Feb;14(2):106-13. doi: 10.1038/nsmb1197. Epub 2007 Jan 21. Nat Struct Mol Biol. 2007. PMID: 17237796

9

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.

Cunningham D, Danley DE, Geoghegan KF, Griffor MC, Hawkins JL, Subashi TA, Varghese AH, Ammirati MJ, Culp JS, Hoth LR, Mansour MN, McGrath KM, Seddon AP, Shenolikar S, Stutzman-Engwall KJ, Warren LC, Xia D, Qiu X. Cunningham D, et al. Among authors: ammirati mj. Nat Struct Mol Biol. 2007 May;14(5):413-9. doi: 10.1038/nsmb1235. Epub 2007 Apr 15. Nat Struct Mol Biol. 2007. PMID: 17435765

10

The 2.0 A crystal structure of the ERalpha ligand-binding domain complexed with lasofoxifene.

Vajdos FF, Hoth LR, Geoghegan KF, Simons SP, LeMotte PK, Danley DE, Ammirati MJ, Pandit J. Vajdos FF, et al. Among authors: ammirati mj. Protein Sci. 2007 May;16(5):897-905. doi: 10.1110/ps.062729207. Protein Sci. 2007. PMID: 17456742 Free PMC article.

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