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Complex chemical signals dictate Ah receptor activation through the gut-lung axis.
Dong F, Murray IA, Annalora A, Coslo D, Desai D, Gowda K, Yang J, Wang D, Koo I, Hao F, Amin SG, Patterson AD, Marcus C, Perdew GH. Dong F, et al. Among authors: amin sg. bioRxiv [Preprint]. 2023 Apr 5:2023.02.22.529529. doi: 10.1101/2023.02.22.529529. bioRxiv. 2023. PMID: 36865156 Free PMC article. Updated. Preprint.
Lead optimization of aryl hydrocarbon receptor ligands for treatment of inflammatory skin disorders.
Rikken G, Smith KJ, van den Brink NJM, Smits JPH, Gowda K, Alnemri A, Kuzu GE, Murray IA, Lin JM, Smits JGA, van Vlijmen-Willems IM, Amin SG, Perdew GH, van den Bogaard EH. Rikken G, et al. Among authors: amin sg. Biochem Pharmacol. 2023 Feb;208:115400. doi: 10.1016/j.bcp.2022.115400. Epub 2022 Dec 24. Biochem Pharmacol. 2023. PMID: 36574884 Free article.
Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation.
Morgan EW, Dong F, Annalora AJ, Murray IA, Wolfe T, Erickson R, Gowda K, Amin SG, Petersen KS, Kris-Etherton PM, Marcus CB, Walk ST, Patterson AD, Perdew GH. Morgan EW, et al. Among authors: amin sg. Int J Tryptophan Res. 2023 Jul 7;16:11786469231182510. doi: 10.1177/11786469231182510. eCollection 2023. Int J Tryptophan Res. 2023. PMID: 37441265 Free PMC article.
Bile salt hydrolase catalyses formation of amine-conjugated bile acids.
Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD. Rimal B, et al. Nature. 2024 Feb;626(8000):859-863. doi: 10.1038/s41586-023-06990-w. Epub 2024 Feb 7. Nature. 2024. PMID: 38326609 Free PMC article.
The underappreciated diversity of bile acid modifications.
Mohanty I, Mannochio-Russo H, Schweer JV, El Abiead Y, Bittremieux W, Xing S, Schmid R, Zuffa S, Vasquez F, Muti VB, Zemlin J, Tovar-Herrera OE, Moraïs S, Desai D, Amin S, Koo I, Turck CW, Mizrahi I, Kris-Etherton PM, Petersen KS, Fleming JA, Huan T, Patterson AD, Siegel D, Hagey LR, Wang M, Aron AT, Dorrestein PC. Mohanty I, et al. Cell. 2024 Mar 28;187(7):1801-1818.e20. doi: 10.1016/j.cell.2024.02.019. Epub 2024 Mar 11. Cell. 2024. PMID: 38471500 Free article.
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