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Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.
Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P. Al-Hasani K, et al. Among authors: ambrosetti d. Dev Cell. 2013 Jul 15;26(1):86-100. doi: 10.1016/j.devcel.2013.05.018. Epub 2013 Jun 27. Dev Cell. 2013. PMID: 23810513 Free article.
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Courtney M, Gjernes E, Druelle N, Ravaud C, Vieira A, Ben-Othman N, Pfeifer A, Avolio F, Leuckx G, Lacas-Gervais S, Burel-Vandenbos F, Ambrosetti D, Hecksher-Sorensen J, Ravassard P, Heimberg H, Mansouri A, Collombat P. Courtney M, et al. Among authors: ambrosetti d. PLoS Genet. 2013 Oct;9(10):e1003934. doi: 10.1371/journal.pgen.1003934. Epub 2013 Oct 31. PLoS Genet. 2013. PMID: 24204325 Free PMC article.
The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.
Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F. Loubiere C, et al. Among authors: ambrosetti d. Sci Rep. 2017 Jul 11;7(1):5040. doi: 10.1038/s41598-017-05052-2. Sci Rep. 2017. PMID: 28698627 Free PMC article.
ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.
Dufies M, Ambrosetti D, Boulakirba S, Calleja A, Savy C, Furstoss N, Zerhouni M, Parola J, Aira-Diaz L, Marchetti S, Orange F, Lacas-Gervais S, Luciano F, Jacquel A, Robert G, Pagès G, Auberger P. Dufies M, et al. Among authors: ambrosetti d. Oncotarget. 2017 Dec 23;9(13):10920-10933. doi: 10.18632/oncotarget.23650. eCollection 2018 Feb 16. Oncotarget. 2017. PMID: 29541386 Free PMC article.
Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients.
Fabbri L, Dufies M, Lacas-Gervais S, Gardie B, Gad-Lapiteau S, Parola J, Nottet N, Meyenberg Cunha de Padua M, Contenti J, Borchiellini D, Ferrero JM, Leclercq NR, Ambrosetti D, Mograbi B, Richard S, Viotti J, Chamorey E, Sadaghianloo N, Rouleau M, Craigen WJ, Mari B, Clavel S, Pagès G, Pouysségur J, Bost F, Mazure NM. Fabbri L, et al. Among authors: ambrosetti d. Theranostics. 2020 Feb 3;10(6):2696-2713. doi: 10.7150/thno.41001. eCollection 2020. Theranostics. 2020. PMID: 32194829 Free PMC article.
GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors.
Chiche J, Reverso-Meinietti J, Mouchotte A, Rubio-Patiño C, Mhaidly R, Villa E, Bossowski JP, Proics E, Grima-Reyes M, Paquet A, Fragaki K, Marchetti S, Briere J, Ambrosetti D, Michiels JF, Molina TJ, Copie-Bergman C, Lehmann-Che J, Peyrottes I, Peyrade F, de Kerviler E, Taillan B, Garnier G, Verhoeyen E, Paquis-Flucklinger V, Shintu L, Delwail V, Delpech-Debiais C, Delarue R, Bosly A, Petrella T, Brisou G, Nadel B, Barbry P, Mounier N, Thieblemont C, Ricci JE. Chiche J, et al. Among authors: ambrosetti d. Cell Metab. 2019 Jun 4;29(6):1243-1257.e10. doi: 10.1016/j.cmet.2019.02.002. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827861 Free article.
120 results