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Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models.
Puliga E, De Bellis C, Vietti Michelina S, Capeloa T, Migliore C, Orrù C, Baiocchi GL, De Manzoni G, Pietrantonio F, Reddavid R, Fumagalli Romario U, Ambrogio C, Corso S, Giordano S. Puliga E, et al. Among authors: ambrogio c. Gastric Cancer. 2024 May;27(3):473-483. doi: 10.1007/s10120-024-01468-8. Epub 2024 Jan 23. Gastric Cancer. 2024. PMID: 38261067 Free PMC article.
How to manage KRAS G12C-mutated advanced non-small-cell lung cancer.
Ricciuti B, Mira A, Andrini E, Scaparone P, Michelina SV, Pecci F, Cantini L, De Giglio A, Lamberti G, Ambrogio C, Metro G. Ricciuti B, et al. Among authors: ambrogio c. Drugs Context. 2022 Nov 16;11:2022-7-4. doi: 10.7573/dic.2022-7-4. eCollection 2022. Drugs Context. 2022. PMID: 36452878 Free PMC article. Review.
Regulation of CD45 phosphatase by oncogenic ALK in anaplastic large cell lymphoma.
Mura G, Karaca Atabay E, Menotti M, Martinengo C, Ambrogio C, Giacomello G, Arigoni M, Olivero M, Calogero RA, Chiarle R, Voena C. Mura G, et al. Among authors: ambrogio c. Front Oncol. 2023 Jan 9;12:1085672. doi: 10.3389/fonc.2022.1085672. eCollection 2022. Front Oncol. 2023. PMID: 36698412 Free PMC article.
Resistance to KRAS G12C Inhibition in Non-small Cell Lung Cancer.
Di Federico A, Ricciotti I, Favorito V, Michelina SV, Scaparone P, Metro G, De Giglio A, Pecci F, Lamberti G, Ambrogio C, Ricciuti B. Di Federico A, et al. Among authors: ambrogio c. Curr Oncol Rep. 2023 Sep;25(9):1017-1029. doi: 10.1007/s11912-023-01436-y. Epub 2023 Jun 28. Curr Oncol Rep. 2023. PMID: 37378881 Review.
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases.
Nicoś M, Harbers L, Patrucco E, Kramer-Drauberg M, Zhang X, Voena C, Kowalczyk A, Bożyk A, Pęksa R, Jarosz B, Szumiło J, Simonetti M, Żuk M, Wasąg B, Reszka K, Duchnowska R, Milanowski J, Chiarle R, Bienko M, Krawczyk P, Jassem J, Ambrogio C, Crosetto N. Nicoś M, et al. Among authors: ambrogio c. JTO Clin Res Rep. 2022 Nov 11;3(12):100435. doi: 10.1016/j.jtocrr.2022.100435. eCollection 2022 Dec. JTO Clin Res Rep. 2022. PMID: 36561283 Free PMC article.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Holderfield M, Lee BJ, Jiang J, Tomlinson A, Seamon KJ, Mira A, Patrucco E, Goodhart G, Dilly J, Gindin Y, Dinglasan N, Wang Y, Lai LP, Cai S, Jiang L, Nasholm N, Shifrin N, Blaj C, Shah H, Evans JW, Montazer N, Lai O, Shi J, Ahler E, Quintana E, Chang S, Salvador A, Marquez A, Cregg J, Liu Y, Milin A, Chen A, Ziv TB, Parsons D, Knox JE, Klomp JE, Roth J, Rees M, Ronan M, Cuevas-Navarro A, Hu F, Lito P, Santamaria D, Aguirre AJ, Waters AM, Der CJ, Ambrogio C, Wang Z, Gill AL, Koltun ES, Smith JAM, Wildes D, Singh M. Holderfield M, et al. Among authors: ambrogio c. Nature. 2024 Apr 8. doi: 10.1038/s41586-024-07205-6. Online ahead of print. Nature. 2024. PMID: 38589574
Cancer Hallmarks: Piecing the Puzzle Together.
Alcolea MP, Alonso-Curbelo D, Ambrogio C, Bullman S, Correia AL, Ernst A, Halbrook CJ, Kelly GL, Lund AW, Quail DF, Ruscetti M, Shema E, Stromnes IM, Tam WL. Alcolea MP, et al. Among authors: ambrogio c. Cancer Discov. 2024 Apr 4;14(4):674-682. doi: 10.1158/2159-8290.CD-24-0097. Cancer Discov. 2024. PMID: 38571410 No abstract available.
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells.
Bergaggio E, Tai WT, Aroldi A, Mecca C, Landoni E, Nüesch M, Mota I, Metovic J, Molinaro L, Ma L, Alvarado D, Ambrogio C, Voena C, Blasco RB, Li T, Klein D, Irvine DJ, Papotti M, Savoldo B, Dotti G, Chiarle R. Bergaggio E, et al. Among authors: ambrogio c. Cancer Cell. 2023 Dec 11;41(12):2100-2116.e10. doi: 10.1016/j.ccell.2023.11.004. Epub 2023 Nov 30. Cancer Cell. 2023. PMID: 38039964
86 results