Ambery C - Search Results

1

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.

Bouazza N, Dokoumetzidis A, Knibbe CAJ, de Wildt SN, Ambery C, De Cock PA, Gasthuys E, Foissac F, Urien S, Hamberg AK, Poggesi I, Zhao W, Vermeulen A, Standing JF, Tréluyer JM; c4c Expert group on Pharmacometrics. Bouazza N, et al. Among authors: ambery c. Br J Clin Pharmacol. 2022 Dec;88(12):4985-4996. doi: 10.1111/bcp.15571. Epub 2022 Nov 8. Br J Clin Pharmacol. 2022. PMID: 36256514 Free article. Review.

2

Pharmacokinetics and pharmacodynamics of GSK961081, a novel inhaled muscarinic antagonist β2 -agonist, and fluticasone propionate administered alone, concurrently and as a combination blend formulation in healthy volunteers.

Norris V, Ambery C, Riley T. Norris V, et al. Among authors: ambery c. Clin Pharmacol Drug Dev. 2014 Jul;3(4):305-13. doi: 10.1002/cpdd.105. Epub 2014 Feb 20. Clin Pharmacol Drug Dev. 2014. PMID: 27128837 Clinical Trial.

3

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Food Effect of Danirixin Hydrobromide Tablets in Japanese Healthy Elderly Participants.

Iida T, Matsuzawa Y, Ogura H, Nagakubo T, Wakamatsu A, Ambery C, Miller BE, Lazaar AL, Numachi Y. Iida T, et al. Among authors: ambery c. Clin Pharmacol Drug Dev. 2019 Nov;8(8):1081-1087. doi: 10.1002/cpdd.693. Epub 2019 May 6. Clin Pharmacol Drug Dev. 2019. PMID: 31056840 Clinical Trial.

4

Pharmacodynamics, pharmacokinetics and safety of GSK2190915, a novel oral anti-inflammatory 5-lipoxygenase-activating protein inhibitor.

Bain G, King CD, Schaab K, Rewolinski M, Norris V, Ambery C, Bentley J, Yamada M, Santini AM, van de Wetering de Rooij J, Stock N, Zunic J, Hutchinson JH, Evans JF. Bain G, et al. Among authors: ambery c. Br J Clin Pharmacol. 2013 Mar;75(3):779-90. doi: 10.1111/j.1365-2125.2012.04386.x. Br J Clin Pharmacol. 2013. PMID: 22803688 Free PMC article. Clinical Trial.

5

Open-Label, Crossover Study to Determine the Pharmacokinetics of Fluticasone Furoate and Batefenterol When Administered Alone, in Combination, or Concurrently.

Ambery C, Young G, Fuller T, Georgiou A, Ramsay D, Puri A, Daley-Yates P. Ambery C, et al. Clin Pharmacol Drug Dev. 2019 Feb;8(2):188-197. doi: 10.1002/cpdd.603. Epub 2018 Aug 2. Clin Pharmacol Drug Dev. 2019. PMID: 30070770 Free PMC article. Clinical Trial.

6

Comparing probabilistic and descriptive analyses of time-dose-toxicity relationship for determining no-observed-adverse-effect level in drug development.

Glatard A, Berges A, Sahota T, Ambery C, Osborne J, Smith R, Hénin E, Chen C. Glatard A, et al. Among authors: ambery c. Toxicol Appl Pharmacol. 2015 Oct 15;288(2):240-8. doi: 10.1016/j.taap.2015.07.022. Epub 2015 Jul 29. Toxicol Appl Pharmacol. 2015. PMID: 26232187

7

Bronchodilation and safety of supratherapeutic doses of salbutamol or ipratropium bromide added to single dose GSK961081 in patients with moderate to severe COPD.

Norris V, Ambery C. Norris V, et al. Among authors: ambery c. Pulm Pharmacol Ther. 2013 Oct;26(5):574-80. doi: 10.1016/j.pupt.2013.03.009. Epub 2013 Mar 21. Pulm Pharmacol Ther. 2013. PMID: 23524017 Clinical Trial.

8

Use of propranolol blockade to explore the pharmacology of GSK961081, a bi-functional bronchodilator, in healthy volunteers: results from two randomized trials.

Norris V, Ambery C. Norris V, et al. Among authors: ambery c. Drugs R D. 2014 Dec;14(4):241-51. doi: 10.1007/s40268-014-0060-x. Drugs R D. 2014. PMID: 25265895 Free PMC article. Clinical Trial.

9

Pharmacodynamics of GSK961081, a bi-functional molecule, in patients with COPD.

Bateman ED, Kornmann O, Ambery C, Norris V. Bateman ED, et al. Among authors: ambery c. Pulm Pharmacol Ther. 2013 Oct;26(5):581-7. doi: 10.1016/j.pupt.2013.03.015. Epub 2013 Mar 26. Pulm Pharmacol Ther. 2013. PMID: 23538170 Clinical Trial.

10

Effects of a FLAP inhibitor, GSK2190915, in asthmatics with high sputum neutrophils.

Chaudhuri R, Norris V, Kelly K, Zhu CQ, Ambery C, Lafferty J, Cameron E, Thomson NC. Chaudhuri R, et al. Among authors: ambery c. Pulm Pharmacol Ther. 2014 Feb;27(1):62-9. doi: 10.1016/j.pupt.2013.11.007. Epub 2013 Dec 10. Pulm Pharmacol Ther. 2014. PMID: 24333186 Clinical Trial.

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