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148 results

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DNMT1-interacting RNAs block gene-specific DNA methylation.
Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Alò F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG. Di Ruscio A, et al. Among authors: amabile g. Nature. 2013 Nov 21;503(7476):371-6. doi: 10.1038/nature12598. Epub 2013 Oct 9. Nature. 2013. PMID: 24107992 Free PMC article.
Dissecting the role of aberrant DNA methylation in human leukaemia.
Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG. Amabile G, et al. Nat Commun. 2015 May 22;6:7091. doi: 10.1038/ncomms8091. Nat Commun. 2015. PMID: 25997600 Free PMC article.
C/EBPα is required for development of dendritic cell progenitors.
Welner RS, Bararia D, Amabile G, Czibere A, Benoukraf T, Bach C, Wansa KD, Ye M, Zhang H, Iino T, Hetherington CJ, Akashi K, Tenen DG. Welner RS, et al. Among authors: amabile g. Blood. 2013 May 16;121(20):4073-81. doi: 10.1182/blood-2012-10-463448. Epub 2013 Apr 1. Blood. 2013. PMID: 23547051 Free PMC article.
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.
Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG. Zhang H, et al. Among authors: amabile g. Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Cancer Cell. 2013. PMID: 24183681 Free PMC article.
The second hit of DNA methylation.
Di Ruscio A, Welner RS, Tenen DG, Amabile G. Di Ruscio A, et al. Among authors: amabile g. Mol Cell Oncol. 2015 Oct 29;3(3):e1093690. doi: 10.1080/23723556.2015.1093690. eCollection 2016 May. Mol Cell Oncol. 2015. PMID: 27314082 Free PMC article.
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
Alberich-Jordà M, Wouters B, Balastik M, Shapiro-Koss C, Zhang H, Di Ruscio A, Radomska HS, Ebralidze AK, Amabile G, Ye M, Zhang J, Lowers I, Avellino R, Melnick A, Figueroa ME, Valk PJ, Delwel R, Tenen DG. Alberich-Jordà M, et al. Among authors: amabile g. J Clin Invest. 2012 Dec;122(12):4490-504. doi: 10.1172/JCI65102. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160200 Free PMC article.
RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.
Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG. Levantini E, et al. Among authors: amabile g. EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285. EMBO J. 2011. PMID: 21873977 Free PMC article.
148 results