Alzarea SI - Search Results

1

Quality by Design (QbD) Based Method for Estimation of Xanthohumol in Bulk and Solid Lipid Nanoparticles and Validation.

Harish V, Almalki WH, Alshehri A, Alzahrani A, Gupta MM, Alzarea SI, Kazmi I, Gulati M, Tewari D, Gupta G, Dua K, Singh SK. Harish V, et al. Among authors: alzarea si. Molecules. 2023 Jan 4;28(2):472. doi: 10.3390/molecules28020472. Molecules. 2023. PMID: 36677532 Free PMC article.

2

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAF^V600E dual inhibitors with potent antiproliferative and antioxidant activities.

Gomaa HAM, Shaker ME, Alzarea SI, Hendawy OM, Mohamed FAM, Gouda AM, Ali AT, Morcoss MM, Abdelrahman MH, Trembleau L, Youssif BGM. Gomaa HAM, et al. Among authors: alzarea si. Bioorg Chem. 2022 Mar;120:105616. doi: 10.1016/j.bioorg.2022.105616. Epub 2022 Jan 19. Bioorg Chem. 2022. PMID: 35078049

3

Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice.

Alzarea S, Rahman S. Alzarea S, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 30;86:218-228. doi: 10.1016/j.pnpbp.2018.05.018. Epub 2018 May 22. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29800595

4

Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain.

Abbas M, Alzarea S, Papke RL, Rahman S. Abbas M, et al. CNS Neurol Disord Drug Targets. 2021;20(4):366-377. doi: 10.2174/1871527319666201230102616. CNS Neurol Disord Drug Targets. 2021. PMID: 33380307

5

Alpha-7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice.

Alzarea S, Rahman S. Alzarea S, et al. Behav Brain Res. 2019 Jul 2;366:19-28. doi: 10.1016/j.bbr.2019.03.019. Epub 2019 Mar 12. Behav Brain Res. 2019. PMID: 30877025

6

The Effect of an α-7 Nicotinic Allosteric Modulator PNU120596 and NMDA Receptor Antagonist Memantine on Depressive-like Behavior Induced by LPS in Mice: The Involvement of Brain Microglia.

Alzarea S, Abbas M, Ronan PJ, Lutfy K, Rahman S. Alzarea S, et al. Brain Sci. 2022 Nov 3;12(11):1493. doi: 10.3390/brainsci12111493. Brain Sci. 2022. PMID: 36358419 Free PMC article.

7

Glial mechanisms underlying major depressive disorder: Potential therapeutic opportunities.

Rahman S, Alzarea S. Rahman S, et al. Prog Mol Biol Transl Sci. 2019;167:159-178. doi: 10.1016/bs.pmbts.2019.06.010. Epub 2019 Jul 13. Prog Mol Biol Transl Sci. 2019. PMID: 31601403 Review.

8

New Cytotoxic Natural Products from the Red Sea Sponge Stylissa carteri.

Abdelhameed RFA, Habib ES, Eltahawy NA, Hassanean HA, Ibrahim AK, Mohammed AF, Fayez S, Hayallah AM, Yamada K, Behery FA, Al-Sanea MM, Alzarea SI, Bringmann G, Ahmed SA, Abdelmohsen UR. Abdelhameed RFA, et al. Among authors: alzarea si. Mar Drugs. 2020 May 3;18(5):241. doi: 10.3390/md18050241. Mar Drugs. 2020. PMID: 32375235 Free PMC article.

9

Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects.

Hendawy OM, Gomaa HAM, Alzarea SI, Alshammari MS, Mohamed FAM, Mostafa YA, Abdelazeem AH, Abdelrahman MH, Trembleau L, Youssif BGM. Hendawy OM, et al. Among authors: alzarea si. Bioorg Chem. 2021 Nov;116:105302. doi: 10.1016/j.bioorg.2021.105302. Epub 2021 Aug 24. Bioorg Chem. 2021. PMID: 34464816

10

The α7 nicotinic acetylcholine receptor positive allosteric modulator prevents lipopolysaccharide-induced allodynia, hyperalgesia and TNF-α in the hippocampus in mice.

Abbas M, Alzarea S, Papke RL, Rahman S. Abbas M, et al. Pharmacol Rep. 2019 Dec;71(6):1168-1176. doi: 10.1016/j.pharep.2019.07.001. Epub 2019 Jul 3. Pharmacol Rep. 2019. PMID: 31655281 Free PMC article.

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