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Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism.
Bayraktar EC, La K, Karpman K, Unlu G, Ozerdem C, Ritter DJ, Alwaseem H, Molina H, Hoffmann HH, Millner A, Atilla-Gokcumen GE, Gamazon ER, Rushing AR, Knapik EW, Basu S, Birsoy K. Bayraktar EC, et al. Among authors: alwaseem h. Nat Metab. 2020 Jun;2(6):487-498. doi: 10.1038/s42255-020-0206-9. Epub 2020 Jun 1. Nat Metab. 2020. PMID: 32694732 Free PMC article.
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Guarecuco R, Williams RT, Baudrier L, La K, Passarelli MC, Ekizoglu N, Mestanoglu M, Alwaseem H, Rostandy B, Fidelin J, Garcia-Bermudez J, Molina H, Birsoy K. Guarecuco R, et al. Among authors: alwaseem h. Sci Adv. 2020 Oct 9;6(41):eabc7120. doi: 10.1126/sciadv.abc7120. Print 2020 Oct. Sci Adv. 2020. PMID: 33036978 Free PMC article.
Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia.
Garcia-Bermudez J, Badgley MA, Prasad S, Baudrier L, Liu Y, La K, Soula M, Williams RT, Yamaguchi N, Hwang RF, Taylor LJ, de Stanchina E, Rostandy B, Alwaseem H, Molina H, Bar-Sagi D, Birsoy K. Garcia-Bermudez J, et al. Among authors: alwaseem h. Nat Metab. 2022 Jun;4(6):724-738. doi: 10.1038/s42255-022-00583-z. Epub 2022 Jun 20. Nat Metab. 2022. PMID: 35726024 Free PMC article.
The pupal moulting fluid has evolved social functions in ants.
Snir O, Alwaseem H, Heissel S, Sharma A, Valdés-Rodríguez S, Carroll TS, Jiang CS, Razzauti J, Kronauer DJC. Snir O, et al. Among authors: alwaseem h. Nature. 2022 Dec;612(7940):488-494. doi: 10.1038/s41586-022-05480-9. Epub 2022 Nov 30. Nature. 2022. PMID: 36450990 Free PMC article.
Disruption of proteome by an oncogenic fusion kinase alters metabolism in fibrolamellar hepatocellular carcinoma.
Levin SN, Tomasini MD, Knox J, Shirani M, Shebl B, Requena D, Clark J, Heissel S, Alwaseem H, Surjan R, Lahasky R, Molina H, Torbenson MS, Lyons B, Migler RD, Coffino P, Simon SM. Levin SN, et al. Among authors: alwaseem h. Sci Adv. 2023 Jun 23;9(25):eadg7038. doi: 10.1126/sciadv.adg7038. Epub 2023 Jun 21. Sci Adv. 2023. PMID: 37343102 Free PMC article.
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior.
Blaze J, Navickas A, Phillips HL, Heissel S, Plaza-Jennings A, Miglani S, Asgharian H, Foo M, Katanski CD, Watkins CP, Pennington ZT, Javidfar B, Espeso-Gil S, Rostandy B, Alwaseem H, Hahn CG, Molina H, Cai DJ, Pan T, Yao WD, Goodarzi H, Haghighi F, Akbarian S. Blaze J, et al. Among authors: alwaseem h. Nat Commun. 2021 Aug 13;12(1):4913. doi: 10.1038/s41467-021-24969-x. Nat Commun. 2021. PMID: 34389722 Free PMC article.
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