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Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, Kauffenstein G, Nakaya HI, Borges MC, Zamboni DS, Fonseca DM, Paschoal JAR, Cunha TM, Quesniaux V, Linden J, Cunha FQ, Ryffel B, Alves-Filho JC. Nascimento DC, et al. Immunity. 2021 Sep 14;54(9):2024-2041.e8. doi: 10.1016/j.immuni.2021.08.005. Epub 2021 Sep 1. Immunity. 2021. PMID: 34473957 Free article.
Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels.
Dal-Secco D, Cunha TM, Freitas A, Alves-Filho JC, Souto FO, Fukada SY, Grespan R, Alencar NM, Neto AF, Rossi MA, Ferreira SH, Hothersall JS, Cunha FQ. Dal-Secco D, et al. J Immunol. 2008 Sep 15;181(6):4287-98. doi: 10.4049/jimmunol.181.6.4287. J Immunol. 2008. PMID: 18768887
Targeting neutrophils in sepsis.
Sônego F, Alves-Filho JC, Cunha FQ. Sônego F, et al. Expert Rev Clin Immunol. 2014 Aug;10(8):1019-28. doi: 10.1586/1744666X.2014.922876. Epub 2014 May 28. Expert Rev Clin Immunol. 2014. PMID: 24867165 Review.
Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis.
Peres RS, Liew FY, Talbot J, Carregaro V, Oliveira RD, Almeida SL, França RF, Donate PB, Pinto LG, Ferreira FI, Costa DL, Demarque DP, Gouvea DR, Lopes NP, Queiroz RH, Silva JS, Figueiredo F, Alves-Filho JC, Cunha TM, Ferreira SH, Louzada-Junior P, Cunha FQ. Peres RS, et al. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2509-14. doi: 10.1073/pnas.1424792112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675517 Free PMC article.
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.
Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Czaikoski PG, et al. PLoS One. 2016 Feb 5;11(2):e0148142. doi: 10.1371/journal.pone.0148142. eCollection 2016. PLoS One. 2016. PMID: 26849138 Free PMC article.
Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious.
Sônego F, Castanheira FV, Ferreira RG, Kanashiro A, Leite CA, Nascimento DC, Colón DF, Borges Vde F, Alves-Filho JC, Cunha FQ. Sônego F, et al. Front Immunol. 2016 Apr 26;7:155. doi: 10.3389/fimmu.2016.00155. eCollection 2016. Front Immunol. 2016. PMID: 27199981 Free PMC article. Review.
222 results