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Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Sandri S, Faião-Flores F, Tiago M, Pennacchi PC, Massaro RR, Alves-Fernandes DK, Berardinelli GN, Evangelista AF, de Lima Vazquez V, Reis RM, Maria-Engler SS. Sandri S, et al. Among authors: alves fernandes dk. Pharmacol Res. 2016 Sep;111:523-533. doi: 10.1016/j.phrs.2016.07.017. Epub 2016 Jul 18. Pharmacol Res. 2016. PMID: 27436149 Free article.
Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.
Faião-Flores F, Alves-Fernandes DK, Pennacchi PC, Sandri S, Vicente AL, Scapulatempo-Neto C, Vazquez VL, Reis RM, Chauhan J, Goding CR, Smalley KS, Maria-Engler SS. Faião-Flores F, et al. Among authors: alves fernandes dk. Oncogene. 2017 Mar 30;36(13):1849-1861. doi: 10.1038/onc.2016.348. Epub 2016 Oct 17. Oncogene. 2017. PMID: 27748762 Free PMC article.
Toxicogenomic and bioinformatics platforms to identify key molecular mechanisms of a curcumin-analogue DM-1 toxicity in melanoma cells.
Oliveira ÉA, Lima DS, Cardozo LE, Souza GF, de Souza N, Alves-Fernandes DK, Faião-Flores F, Quincoces JAP, Barros SBM, Nakaya HI, Monteiro G, Maria-Engler SS. Oliveira ÉA, et al. Among authors: alves fernandes dk. Pharmacol Res. 2017 Nov;125(Pt B):178-187. doi: 10.1016/j.phrs.2017.08.018. Epub 2017 Sep 4. Pharmacol Res. 2017. PMID: 28882690
Survivin modulation in the antimelanoma activity of prodiginines.
Branco PC, Pontes CA, Rezende-Teixeira P, Amengual-Rigo P, Alves-Fernandes DK, Maria-Engler SS, da Silva AB, Pessoa ODL, Jimenez PC, Mollasalehi N, Chapman E, Guallar V, Machado-Neto JA, Costa-Lotufo LV. Branco PC, et al. Among authors: alves fernandes dk. Eur J Pharmacol. 2020 Dec 5;888:173465. doi: 10.1016/j.ejphar.2020.173465. Epub 2020 Aug 16. Eur J Pharmacol. 2020. PMID: 32814079 Free article.
miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients.
da Cruz AT, Hunger A, de Melo FHM, Monteiro AC, Paré GC, Lai D, Alves-Fernandes DK, Ayub ALP, Cordero EM, Filho JFDS, Schneider-Stock R, Strauss BE, Tron V, Jasiulionis MG. da Cruz AT, et al. Among authors: alves fernandes dk. Neoplasia. 2021 Aug;23(8):823-834. doi: 10.1016/j.neo.2021.05.015. Epub 2021 Jul 8. Neoplasia. 2021. PMID: 34246986 Free PMC article.