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Bioactive Compounds as Potential Agents for Sexually Transmitted Diseases Management: A Review to Explore Molecular Mechanisms of Action.
Sharifi-Rad J, Quispe C, Rahavian A, Pereira Carneiro JN, Rocha JE, Alves Borges Leal AL, Bezerra Morais Braga MF, Melo Coutinho HD, Ansari Djafari A, Alarcón-Zapata P, Martorell M, Antika G, Tumer TB, Cruz-Martins N, Helon P, Paprocka P, Koch W, Docea AO, Calina D. Sharifi-Rad J, et al. Among authors: alves borges leal al. Front Pharmacol. 2021 Aug 24;12:674682. doi: 10.3389/fphar.2021.674682. eCollection 2021. Front Pharmacol. 2021. PMID: 34504422 Free PMC article. Review.
Chemical identification and antimicrobial potential of essential oil of Piper rivinoides kunth (BETIS-WHITE).
Alves Borges Leal AL, Machado AJT, Bezerra CF, Serra Inácio CE, Rocha JE, Sales DL, de Freitas TS, de Oliveira Almeida W, Amaral WD, Everson da Silva L, Ferriani AP, de Noronha Sales Maia BHL, Bezerra Morais-Braga MF, Barreto HM, Coutinho HDM. Alves Borges Leal AL, et al. Food Chem Toxicol. 2019 Sep;131:110559. doi: 10.1016/j.fct.2019.06.006. Epub 2019 Jun 7. Food Chem Toxicol. 2019. PMID: 31176927
Seasonal variation of the composition of essential oils from Piper cernuum Vell and Piper rivinoides Kunth, ADMET study, DFT calculations, molecular docking and dynamics studies of major components as potent inhibitors of the heterodimer methyltransferase complex NSP16-NSP10 SARS COV-2 protein.
Alves Borges Leal AL, Fonseca Bezerra C, Ferreira E Silva AK, Everson da Silva L, Bezerra LL, Almeida-Neto FW, Marinho EM, Celedonio Fernandes CF, Nunes da Rocha M, Marinho MM, Coutinho HDM, Barreto HM, Rafaela Freitas Dotto A, Amaral WD, Santos HSD, Lima-Neto P, Marinho ES. Alves Borges Leal AL, et al. J Biomol Struct Dyn. 2023 Aug-Sep;41(13):6326-6344. doi: 10.1080/07391102.2022.2107072. Epub 2022 Aug 9. J Biomol Struct Dyn. 2023. PMID: 35943030
Potentiating activity of Norfloxacin by synthetic chalcones against NorA overproducing Staphylococcus aureus.
Alves Borges Leal AL, Teixeira da Silva P, Nunes da Rocha M, Marinho EM, Marinho ES, Marinho MM, Bandeira PN, Sampaio Nogueira CE, Barreto HM, Rodrigues Teixeira AM, Silva Dos Santos H. Alves Borges Leal AL, et al. Microb Pathog. 2021 Jun;155:104894. doi: 10.1016/j.micpath.2021.104894. Epub 2021 Apr 21. Microb Pathog. 2021. PMID: 33894291 Review.
Inhibition of the NorA efflux pump of S. aureus by (Z)-5-(4-Fluorobenzylidene)-Imidazolidines.
Faillace MS, Alves Borges Leal AL, Araújo de Oliveira Alcântara F, Ferreira JHL, de Siqueira-Júnior JP, Sampaio Nogueira CE, Barreto HM, Peláez WJ. Faillace MS, et al. Among authors: alves borges leal al. Bioorg Med Chem Lett. 2021 Jan 1;31:127670. doi: 10.1016/j.bmcl.2020.127670. Epub 2020 Nov 6. Bioorg Med Chem Lett. 2021. PMID: 33161124
Antifungal effect of the liposome encapsulation of the Trans- Caryophylene and its association with fluconazole.
Bezerra CF, Geraldo de Alencar Júnior J, de Lima Honorato R, Lucas Dos Santos AT, Pereira da Silva JC, Gusmão da Silva T, Sampaio de Freitas T, Fonseca Bezerra MC, Alves Borges Leal AL, Sales DL, Viana Rodrigues JP, Barbosa Filho JM, Peixoto LR, Pinheiro AP, Melo Coutinho HD, Bezerra Morais-Braga MF, Gonçalves da Silva T. Bezerra CF, et al. Among authors: alves borges leal al. Chem Biol Interact. 2023 Mar 1;373:110377. doi: 10.1016/j.cbi.2023.110377. Epub 2023 Feb 6. Chem Biol Interact. 2023. PMID: 36754224