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Experimental factors that impact CaV1.2 channel pharmacology-Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the "step-step-ramp" voltage protocol.
Ren M, Randolph AL, Alvarez-Baron C, Guo D, Tran PN, Thiebaud N, Sheng J, Zhao J, Wu WW. Ren M, et al. Among authors: alvarez baron c. PLoS One. 2022 Nov 23;17(11):e0276995. doi: 10.1371/journal.pone.0276995. eCollection 2022. PLoS One. 2022. PMID: 36417390 Free PMC article.
hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
Alvarez Baron C, Thiebaud N, Ren M, Viatchenko-Karpinski S, Indapurkar A, King T, Matta MK, Ismaiel OA, Patel V, Mashaee M, Vicente J, Wu WW. Alvarez Baron C, et al. J Pharmacol Toxicol Methods. 2022 Sep-Oct;117:107193. doi: 10.1016/j.vascn.2022.107193. Epub 2022 Jul 2. J Pharmacol Toxicol Methods. 2022. PMID: 35792285 Free article.
Determination of five positive control drugs in hERG external solution (buffer) by LC-MS/MS to support in vitro hERG assay as recommended by ICH S7B.
King TI, Indapurkar A, Tariq I, DePalma R, Mistry S, Alvarez-Baron C, Ismaiel OA, Wu W, Chiu K, Patel V, Rouse R, Strauss DG, Matta MK. King TI, et al. Among authors: alvarez baron c. J Pharmacol Toxicol Methods. 2022 Nov-Dec;118:107229. doi: 10.1016/j.vascn.2022.107229. Epub 2022 Nov 9. J Pharmacol Toxicol Methods. 2022. PMID: 36334898 Free article.
Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure.
Lang D, Ni H, Medvedev RY, Liu F, Alvarez-Baron CP, Tyan L, Turner DGP, Warden A, Morotti S, Schrauth TA, Rickert C, Proenza C, Chanda B, Kamp TJ, Robertson GA, Grandi E, Glukhov AV. Lang D, et al. Among authors: alvarez baron cp. bioRxiv [Preprint]. 2024 Apr 17:2024.04.14.589457. doi: 10.1101/2024.04.14.589457. bioRxiv. 2024. PMID: 38659841 Free PMC article. Preprint.
Bipolar switching by HCN voltage sensor underlies hyperpolarization activation.
Cowgill J, Klenchin VA, Alvarez-Baron C, Tewari D, Blair A, Chanda B. Cowgill J, et al. Among authors: alvarez baron c. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):670-678. doi: 10.1073/pnas.1816724116. Epub 2018 Dec 26. Proc Natl Acad Sci U S A. 2019. PMID: 30587580 Free PMC article.
Theory of Inpatient Circadian Care (TICC): A Proposal for a Middle-Range Theory.
Camargo-Sanchez A, Niño CL, Sánchez L, Echeverri S, Gutiérrez DP, Duque AF, Pianeta O, Jaramillo-Gómez JA, Pilonieta MA, Cataño N, Arboleda H, Agostino PV, Alvarez-Baron CP, Vargas R. Camargo-Sanchez A, et al. Among authors: alvarez baron cp. Open Nurs J. 2015 Feb 27;9:1-9. doi: 10.2174/1874434601509010001. eCollection 2015. Open Nurs J. 2015. PMID: 25767632 Free PMC article.