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The interaction of sodium trimetaphosphate with collagen I induces conformational change and mineralization that prevents collagenase proteolytic attack.
Carvalho RG, Alvarez MMP, de Sá Oliveira T, Polassi MR, Vilhena FV, Alves FL, Nakaie CR, Nascimento FD, D'Alpino PHP, Tersariol ILDS. Carvalho RG, et al. Among authors: alvarez mmp. Dent Mater. 2020 Jun;36(6):e184-e193. doi: 10.1016/j.dental.2020.03.023. Epub 2020 Apr 15. Dent Mater. 2020. PMID: 32305153
PAR-1 and PAR-2 Expression Is Enhanced in Inflamed Odontoblast Cells.
Alvarez MMP, Moura GE, Machado MFM, Viana GM, de Souza Costa CA, Tjäderhane L, Nader HB, Tersariol ILS, Nascimento FD. Alvarez MMP, et al. J Dent Res. 2017 Dec;96(13):1518-1525. doi: 10.1177/0022034517719415. Epub 2017 Jul 31. J Dent Res. 2017. PMID: 28759300