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Page 1
Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition.
Potts KS, Cameron RC, Metidji A, Ghazale N, Wallace L, Leal-Cervantes AI, Palumbo R, Barajas JM, Gupta V, Aluri S, Pradhan K, Myers JA, McKinstry M, Bai X, Choudhary GS, Shastri A, Verma A, Obeng EA, Bowman TV. Potts KS, et al. Among authors: aluri s. Cell Rep. 2022 Dec 13;41(11):111825. doi: 10.1016/j.celrep.2022.111825. Cell Rep. 2022. PMID: 36516770 Free PMC article.
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.
Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kwak C, Choudhary GS, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, Bhagat P, Yu Y, Bartenstein M, Giricz O, Suzuki M, Sohal D, Gupta S, Guerrero PA, Batra S, Goggins M, Steidl U, Greally J, Agarwal B, Pradhan K, Banerjee D, Nagrath D, Maitra A, Verma A. Bhagat TD, et al. Among authors: aluri s. Elife. 2019 Nov 1;8:e50663. doi: 10.7554/eLife.50663. Elife. 2019. PMID: 31663852 Free PMC article.
Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias.
Sridharan A, Schinke CD, Georgiev G, Da Silva Ferreira M, Thiruthuvanathan V, MacArthur I, Bhagat TD, Choudhary GS, Aluri S, Chen J, Pradhan K, Xia Y, Panjikaran M, Sims G, Bhagat CK, Bender R, Keeler L, Graber A, Heuck C, Fletcher FA, Alapat D, Weinhold N, Johnson SK, Wickrema A, Barlogie B, Morgan GJ, Shastri A, Steidl U, Will B, Verma A. Sridharan A, et al. Among authors: aluri s. Blood Adv. 2019 Dec 10;3(23):3962-3967. doi: 10.1182/bloodadvances.2019000731. Blood Adv. 2019. PMID: 31805192 Free PMC article.
The thrombopoietin mimetic JNJ-26366821 increases megakaryopoiesis without affecting malignant myeloid proliferation.
Adrianzen-Herrera D, Choudhary G, Gordon-Mitchell S, Ramachandra N, Bhagat T, Zhang H, Aluri S, Shastri A, Steidl U, Will B, Yang WL, Mahler M, Eichenbaum G, Guha C, Verma A. Adrianzen-Herrera D, et al. Among authors: aluri s. Leuk Lymphoma. 2020 Oct;61(10):2453-2465. doi: 10.1080/10428194.2020.1775213. Epub 2020 Jun 24. Leuk Lymphoma. 2020. PMID: 32578476
Methylation of dual-specificity phosphatase 4 controls cell differentiation.
Su H, Jiang M, Senevirathne C, Aluri S, Zhang T, Guo H, Xavier-Ferrucio J, Jin S, Tran NT, Liu SM, Sun CW, Zhu Y, Zhao Q, Chen Y, Cable L, Shen Y, Liu J, Qu CK, Han X, Klug CA, Bhatia R, Chen Y, Nimer SD, Zheng YG, Iancu-Rubin C, Jin J, Deng H, Krause DS, Xiang J, Verma A, Luo M, Zhao X. Su H, et al. Among authors: aluri s. Cell Rep. 2021 Jul 27;36(4):109421. doi: 10.1016/j.celrep.2021.109421. Cell Rep. 2021. PMID: 34320342 Free PMC article.
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster.
Jasra S, Giricz O, Zeig-Owens R, Pradhan K, Goldfarb DG, Barreto-Galvez A, Silver AJ, Chen J, Sahu S, Gordon-Mitchell S, Choudhary GS, Aluri S, Bhagat TD, Shastri A, Bejan CA, Stockton SS, Spaulding TP, Thiruthuvanathan V, Goto H, Gerhardt J, Haider SH, Veerappan A, Bartenstein M, Nwankwo G, Landgren O, Weiden MD, Lekostaj J, Bender R, Fletcher F, Greenberger L, Ebert BL, Steidl U, Will B, Nolan A, Madireddy A, Savona MR, Prezant DJ, Verma A. Jasra S, et al. Among authors: aluri s. Nat Med. 2022 Mar;28(3):468-471. doi: 10.1038/s41591-022-01708-3. Epub 2022 Mar 7. Nat Med. 2022. PMID: 35256801 Free PMC article.
Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer.
Zhang Y, Chen X, Wang H, Gordon-Mitchell S, Sahu S, Bhagat TD, Choudhary G, Aluri S, Pradhan K, Sahu P, Carbajal M, Zhang H, Agarwal B, Shastri A, Martell R, Starczynowski D, Steidl U, Maitra A, Verma A. Zhang Y, et al. Among authors: aluri s. J Hematol Oncol. 2022 May 23;15(1):70. doi: 10.1186/s13045-022-01286-4. J Hematol Oncol. 2022. PMID: 35606824 Free PMC article.
Correction: Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer.
Zhang Y, Chen X, Wang H, Gordon-Mitchell S, Sahu S, Bhagat TD, Choudhary G, Aluri S, Pradhan K, Sahu P, Carbajal M, Zhang H, Agarwal B, Shastri A, Martell R, Starczynowski D, Steidl U, Maitra A, Verma A. Zhang Y, et al. Among authors: aluri s. J Hematol Oncol. 2022 Jul 26;15(1):100. doi: 10.1186/s13045-022-01321-4. J Hematol Oncol. 2022. PMID: 35883108 Free PMC article. No abstract available.
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
Choudhary GS, Pellagatti A, Agianian B, Smith MA, Bhagat TD, Gordon-Mitchell S, Sahu S, Pandey S, Shah N, Aluri S, Aggarwal R, Aminov S, Schwartz L, Steeples V, Booher RN, Ramachandra M, Samson M, Carbajal M, Pradhan K, Bowman TV, Pillai MM, Will B, Wickrema A, Shastri A, Bradley RK, Martell RE, Steidl UG, Gavathiotis E, Boultwood J, Starczynowski DT, Verma A. Choudhary GS, et al. Among authors: aluri s. Elife. 2022 Aug 30;11:e78136. doi: 10.7554/eLife.78136. Elife. 2022. PMID: 36040792 Free PMC article.
57 results