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Combined HAT/EZH2 modulation leads to cancer-selective cell death.
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-Megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L. Petraglia F, et al. Among authors: altucci l. Oncotarget. 2018 May 22;9(39):25630-25646. doi: 10.18632/oncotarget.25428. eCollection 2018 May 22. Oncotarget. 2018. PMID: 29876013 Free PMC article.
Inhibition of human breast cancer cell growth by blockade of the mevalonate-protein prenylation pathway is not prevented by overexpression of cyclin D1.
Germano D, Pacilio C, Cancemi M, Cicatiello L, Altucci L, Petrizzi VB, Sperandio C, Salzano S, Michalides RJ, Taya Y, Bresciani F, Weisz A. Germano D, et al. Among authors: altucci l. Breast Cancer Res Treat. 2001 May;67(1):23-33. doi: 10.1023/a:1010675310188. Breast Cancer Res Treat. 2001. PMID: 11518463
Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter.
Cicatiello L, Addeo R, Sasso A, Altucci L, Petrizzi VB, Borgo R, Cancemi M, Caporali S, Caristi S, Scafoglio C, Teti D, Bresciani F, Perillo B, Weisz A. Cicatiello L, et al. Among authors: altucci l. Mol Cell Biol. 2004 Aug;24(16):7260-74. doi: 10.1128/MCB.24.16.7260-7274.2004. Mol Cell Biol. 2004. PMID: 15282324 Free PMC article.
Acute myeloid leukemia: therapeutic impact of epigenetic drugs.
Altucci L, Clarke N, Nebbioso A, Scognamiglio A, Gronemeyer H. Altucci L, et al. Int J Biochem Cell Biol. 2005 Sep;37(9):1752-62. doi: 10.1016/j.biocel.2005.04.019. Int J Biochem Cell Biol. 2005. PMID: 15964234 Review.
TRAIL: at the center of drugable anti-tumor pathways.
Clarke N, Nebbioso A, Altucci L, Gronemeyer H. Clarke N, et al. Among authors: altucci l. Cell Cycle. 2005 Jul;4(7):914-8. doi: 10.4161/cc.4.7.1822. Epub 2005 Jul 5. Cell Cycle. 2005. PMID: 15970670 Review.
Piroxicam and cisplatin in a mouse model of peritoneal mesothelioma.
Spugnini EP, Cardillo I, Verdina A, Crispi S, Saviozzi S, Calogero R, Nebbioso A, Altucci L, Cortese G, Galati R, Chien J, Shridhar V, Vincenzi B, Citro G, Cognetti F, Sacchi A, Baldi A. Spugnini EP, et al. Among authors: altucci l. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6133-43. doi: 10.1158/1078-0432.CCR-06-1056. Clin Cancer Res. 2006. PMID: 17062690
344 results