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Page 1
Opportunities and challenges for the computational interpretation of rare variation in clinically important genes.
McInnes G, Sharo AG, Koleske ML, Brown JEH, Norstad M, Adhikari AN, Wang S, Brenner SE, Halpern J, Koenig BA, Magnus DC, Gallagher RC, Giacomini KM, Altman RB. McInnes G, et al. Among authors: altman rb. Am J Hum Genet. 2021 Apr 1;108(4):535-548. doi: 10.1016/j.ajhg.2021.03.003. Am J Hum Genet. 2021. PMID: 33798442 Free PMC article. Review.
Pharmacogenomics: challenges and opportunities.
Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST; Pharmacogenetics Research Network. Roden DM, et al. Among authors: altman rb. Ann Intern Med. 2006 Nov 21;145(10):749-57. doi: 10.7326/0003-4819-145-10-200611210-00007. Ann Intern Med. 2006. PMID: 17116919 Free PMC article. Review.
Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing.
Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, Roden D, Krauss RM, Ratain M. Altman RB, et al. Pharmacogenomics. 2007 May;8(5):519. doi: 10.2217/14622416.8.5.519. Pharmacogenomics. 2007. PMID: 17465717 Free article. No abstract available.
SLC19A1 pharmacogenomics summary.
Yee SW, Gong L, Badagnani I, Giacomini KM, Klein TE, Altman RB. Yee SW, et al. Among authors: altman rb. Pharmacogenet Genomics. 2010 Nov;20(11):708-15. doi: 10.1097/FPC.0b013e32833eca92. Pharmacogenet Genomics. 2010. PMID: 20811316 Free PMC article. No abstract available.
Metformin pathways: pharmacokinetics and pharmacodynamics.
Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE. Gong L, et al. Among authors: altman rb. Pharmacogenet Genomics. 2012 Nov;22(11):820-7. doi: 10.1097/FPC.0b013e3283559b22. Pharmacogenet Genomics. 2012. PMID: 22722338 Free PMC article. Review. No abstract available.
PharmGKB summary: very important pharmacogene information for SLC22A1.
Goswami S, Gong L, Giacomini K, Altman RB, Klein TE. Goswami S, et al. Among authors: altman rb. Pharmacogenet Genomics. 2014 Jun;24(6):324-8. doi: 10.1097/FPC.0000000000000048. Pharmacogenet Genomics. 2014. PMID: 24681965 Free PMC article. No abstract available.
Unmet needs: Research helps regulators do their jobs.
Altman RB, Khuri N, Salit M, Giacomini KM. Altman RB, et al. Sci Transl Med. 2015 Nov 25;7(315):315ps22. doi: 10.1126/scitranslmed.aac4369. Sci Transl Med. 2015. PMID: 26606966 Review.
544 results