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Page 1
Scientific considerations for global drug development.
Wilson JL, Cheung KWK, Lin L, Green EAE, Porrás AI, Zou L, Mukanga D, Akpa PA, Darko DM, Yuan R, Ding S, Johnson WCN, Lee HA, Cooke E, Peck CC, Kern SE, Hartman D, Hayashi Y, Marks PW, Altman RB, Lumpkin MM, Giacomini KM, Blaschke TF. Wilson JL, et al. Among authors: altman rb. Sci Transl Med. 2020 Jul 29;12(554):eaax2550. doi: 10.1126/scitranslmed.aax2550. Sci Transl Med. 2020. PMID: 32727913 Free PMC article. Review.
SLC19A1 pharmacogenomics summary.
Yee SW, Gong L, Badagnani I, Giacomini KM, Klein TE, Altman RB. Yee SW, et al. Among authors: altman rb. Pharmacogenet Genomics. 2010 Nov;20(11):708-15. doi: 10.1097/FPC.0b013e32833eca92. Pharmacogenet Genomics. 2010. PMID: 20811316 Free PMC article. No abstract available.
Metformin pathways: pharmacokinetics and pharmacodynamics.
Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE. Gong L, et al. Among authors: altman rb. Pharmacogenet Genomics. 2012 Nov;22(11):820-7. doi: 10.1097/FPC.0b013e3283559b22. Pharmacogenet Genomics. 2012. PMID: 22722338 Free PMC article. Review. No abstract available.
PharmGKB summary: very important pharmacogene information for SLC22A1.
Goswami S, Gong L, Giacomini K, Altman RB, Klein TE. Goswami S, et al. Among authors: altman rb. Pharmacogenet Genomics. 2014 Jun;24(6):324-8. doi: 10.1097/FPC.0000000000000048. Pharmacogenet Genomics. 2014. PMID: 24681965 Free PMC article. No abstract available.
Unmet needs: Research helps regulators do their jobs.
Altman RB, Khuri N, Salit M, Giacomini KM. Altman RB, et al. Sci Transl Med. 2015 Nov 25;7(315):315ps22. doi: 10.1126/scitranslmed.aac4369. Sci Transl Med. 2015. PMID: 26606966 Review.
A research roadmap for next-generation sequencing informatics.
Altman RB, Prabhu S, Sidow A, Zook JM, Goldfeder R, Litwack D, Ashley E, Asimenos G, Bustamante CD, Donigan K, Giacomini KM, Johansen E, Khuri N, Lee E, Liang XS, Salit M, Serang O, Tezak Z, Wall DP, Mansfield E, Kass-Hout T. Altman RB, et al. Sci Transl Med. 2016 Apr 20;8(335):335ps10. doi: 10.1126/scitranslmed.aaf7314. Sci Transl Med. 2016. PMID: 27099173 Free PMC article. Review.
PharmGKB summary: very important pharmacogene information for ABCG2.
Fohner AE, Brackman DJ, Giacomini KM, Altman RB, Klein TE. Fohner AE, et al. Among authors: altman rb. Pharmacogenet Genomics. 2017 Nov;27(11):420-427. doi: 10.1097/FPC.0000000000000305. Pharmacogenet Genomics. 2017. PMID: 28858993 Free PMC article. Review. No abstract available.
544 results