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Neutrophils are mediators of metastatic prostate cancer progression in bone.
Costanzo-Garvey DL, Keeley T, Case AJ, Watson GF, Alsamraae M, Yu Y, Su K, Heim CE, Kielian T, Morrissey C, Frieling JS, Cook LM. Costanzo-Garvey DL, et al. Among authors: alsamraae m. Cancer Immunol Immunother. 2020 Jun;69(6):1113-1130. doi: 10.1007/s00262-020-02527-6. Epub 2020 Feb 29. Cancer Immunol Immunother. 2020. PMID: 32114681 Free PMC article.
Prostate cancer addiction to oxidative stress defines sensitivity to anti-tumor neutrophils.
Costanzo-Garvey DL, Case AJ, Watson GF, Alsamraae M, Chatterjee A, Oberley-Deegan RE, Dutta S, Abdalla MY, Kielian T, Lindsey ML, Cook LM. Costanzo-Garvey DL, et al. Among authors: alsamraae m. Clin Exp Metastasis. 2022 Aug;39(4):641-659. doi: 10.1007/s10585-022-10170-x. Epub 2022 May 23. Clin Exp Metastasis. 2022. PMID: 35604506 Free PMC article.
Androgen receptor inhibition suppresses anti-tumor neutrophil response against bone metastatic prostate cancer via regulation of TβRI expression.
Alsamraae M, Costanzo-Garvey D, Teply BA, Boyle S, Sommerville G, Herbert ZT, Morrissey C, Dafferner AJ, Abdalla MY, Fallet RW, Kielian T, Jensen-Smith H, deOliveira EI, Chen K, Bettencourt IA, Wang JM, McVicar DW, Keeley T, Yu F, Cook LM. Alsamraae M, et al. Cancer Lett. 2023 Nov 28;579:216468. doi: 10.1016/j.canlet.2023.216468. Epub 2023 Nov 7. Cancer Lett. 2023. PMID: 37940068 Free article.