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Metformin and thymoquinone co-treatment enhance 5-fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
Farrash WF, Aslam A, Almaimani R, Minshawi F, Almasmoum H, Alsaegh A, Iqbal MS, Tabassum A, Elzubier ME, El-Readi MZ, Mahbub AA, Idris S, Refaat B. Farrash WF, et al. Among authors: alsaegh a. Biofactors. 2023 Jul-Aug;49(4):831-848. doi: 10.1002/biof.1947. Epub 2023 Mar 16. Biofactors. 2023. PMID: 36929658
Chemopreventive effects of vitamin D3 and its analogue, paricalcitol, in combination with 5-fluorouracil against colorectal cancer: The role of calcium signalling molecules.
Aslam A, Ahmad J, Baghdadi MA, Idris S, Almaimani R, Alsaegh A, Alhadrami M, Refaat B. Aslam A, et al. Biochim Biophys Acta Mol Basis Dis. 2021 Mar 1;1867(3):166040. doi: 10.1016/j.bbadis.2020.166040. Epub 2020 Dec 16. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33338596 Free article.
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