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Design, synthesis, and evaluation of l-cystine diamides as l-cystine crystallization inhibitors for cystinuria.
Bioorg Med Chem Lett. 2018 May 1;28(8):1303-1308. doi: 10.1016/j.bmcl.2018.03.024. Epub 2018 Mar 10.
Bioorg Med Chem Lett. 2018.
PMID: 29571572
Free PMC article.
l-Cystine Diamides as l-Cystine Crystallization Inhibitors for Cystinuria.
Hu L, Yang Y, Aloysius H, Albanyan H, Yang M, Liang JJ, Yu A, Shtukenberg A, Poloni LN, Kholodovych V, Tischfield JA, Goldfarb DS, Ward MD, Sahota A.
Hu L, et al. Among authors: aloysius h.
J Med Chem. 2016 Aug 11;59(15):7293-8. doi: 10.1021/acs.jmedchem.6b00647. Epub 2016 Jul 26.
J Med Chem. 2016.
PMID: 27409142
Free PMC article.
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Targeted prodrug approaches for hormone refractory prostate cancer.
Aloysius H, Hu L.
Aloysius H, et al.
Med Res Rev. 2015 May;35(3):554-85. doi: 10.1002/med.21333. Epub 2014 Dec 22.
Med Res Rev. 2015.
PMID: 25529338
Review.
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Improving the Specificity of the Prostate-Specific Antigen Substrate Glutaryl-Hyp-Ala-Ser-Chg-Gln as a Promoiety.
Aloysius H, Hu L.
Aloysius H, et al.
Chem Biol Drug Des. 2015 Oct;86(4):837-48. doi: 10.1111/cbdd.12559. Epub 2015 Apr 9.
Chem Biol Drug Des. 2015.
PMID: 25777622
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A novel high-yield synthesis of aminoacyl p-nitroanilines and aminoacyl 7-amino-4-methylcoumarins: Important synthons for the synthesis of chromogenic/fluorogenic protease substrates.
Wu X, Chen Y, Aloysius H, Hu L.
Wu X, et al. Among authors: aloysius h.
Beilstein J Org Chem. 2011;7:1030-5. doi: 10.3762/bjoc.7.117. Epub 2011 Jul 27.
Beilstein J Org Chem. 2011.
PMID: 21915204
Free PMC article.
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Metabolic activation and major protein target of a 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonist.
Aloysius H, Tong VW, Yabut J, Bradley SA, Shang J, Zou Y, Tschirret-Guth RA.
Aloysius H, et al.
Chem Res Toxicol. 2012 Jul 16;25(7):1412-22. doi: 10.1021/tx300017s. Epub 2012 Jul 5.
Chem Res Toxicol. 2012.
PMID: 22765480
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Comparative disposition and metabolism of paraherquamide in sheep, gerbils, and dogs.
Aloysius HA, Elipe MV, Arison BH, Faidley TD, Michael BF, Blizzard TA, Thompson DR, Shoop WL, Tschirret-Guth RA.
Aloysius HA, et al.
Drug Metab Dispos. 2008 Aug;36(8):1659-69. doi: 10.1124/dmd.107.019430. Epub 2008 May 27.
Drug Metab Dispos. 2008.
PMID: 18505789
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TPX-0131, a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations.
Murray BW, Zhai D, Deng W, Zhang X, Ung J, Nguyen V, Zhang H, Barrera M, Parra A, Cowell J, Lee DJ, Aloysius H, Rogers E.
Murray BW, et al. Among authors: aloysius h.
Mol Cancer Ther. 2021 Sep;20(9):1499-1507. doi: 10.1158/1535-7163.MCT-21-0221. Epub 2021 Jun 22.
Mol Cancer Ther. 2021.
PMID: 34158340
Free PMC article.
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