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In vivo hypermutation and continuous evolution.
Nat Rev Methods Primers. 2022;2:37. doi: 10.1038/s43586-022-00130-w. Epub 2022 May 19.
Nat Rev Methods Primers. 2022.
PMID: 37073402
Free PMC article.
No abstract available.
Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities.
Rix G, Watkins-Dulaney EJ, Almhjell PJ, Boville CE, Arnold FH, Liu CC.
Rix G, et al. Among authors: almhjell pj.
Nat Commun. 2020 Nov 6;11(1):5644. doi: 10.1038/s41467-020-19539-6.
Nat Commun. 2020.
PMID: 33159067
Free PMC article.
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Engineering enzymes for noncanonical amino acid synthesis.
Almhjell PJ , Boville CE , Arnold FH .
Almhjell PJ , et al.
Chem Soc Rev. 2018 Dec 21;47(24):8980-8997. doi: 10.1039/c8cs00665b. Epub 2018 Oct 3.
Chem Soc Rev. 2018.
PMID: 30280154
Free PMC article.
Review.
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Direct Enzymatic Synthesis of a Deep-Blue Fluorescent Noncanonical Amino Acid from Azulene and Serine.
Watkins EJ, Almhjell PJ, Arnold FH.
Watkins EJ, et al. Among authors: almhjell pj.
Chembiochem. 2020 Jan 15;21(1-2):80-83. doi: 10.1002/cbic.201900497. Epub 2019 Nov 18.
Chembiochem. 2020.
PMID: 31513332
Free PMC article.
Item in Clipboard
evSeq: Cost-Effective Amplicon Sequencing of Every Variant in a Protein Library.
Wittmann BJ, Johnston KE, Almhjell PJ, Arnold FH.
Wittmann BJ, et al. Among authors: almhjell pj.
ACS Synth Biol. 2022 Mar 18;11(3):1313-1324. doi: 10.1021/acssynbio.1c00592. Epub 2022 Feb 17.
ACS Synth Biol. 2022.
PMID: 35172576
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Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima.
Boville CE, Romney DK, Almhjell PJ, Sieben M, Arnold FH.
Boville CE, et al. Among authors: almhjell pj.
J Org Chem. 2018 Jul 20;83(14):7447-7452. doi: 10.1021/acs.joc.8b00517. Epub 2018 Apr 27.
J Org Chem. 2018.
PMID: 29651849
Free PMC article.
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Metal-chelating non-canonical amino acids in metalloprotein engineering and design.
Almhjell PJ, Mills JH.
Almhjell PJ, et al.
Curr Opin Struct Biol. 2018 Aug;51:170-176. doi: 10.1016/j.sbi.2018.06.001. Epub 2018 Jul 3.
Curr Opin Struct Biol. 2018.
PMID: 29980106
Review.
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Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.
Mills JH, Sheffler W, Ener ME, Almhjell PJ, Oberdorfer G, Pereira JH, Parmeggiani F, Sankaran B, Zwart PH, Baker D.
Mills JH, et al. Among authors: almhjell pj.
Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15012-15017. doi: 10.1073/pnas.1600188113. Epub 2016 Dec 8.
Proc Natl Acad Sci U S A. 2016.
PMID: 27940918
Free PMC article.
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