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Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA. Moraes ADTO, et al. Among authors: almeida smv. Bioorg Med Chem. 2018 Nov 1;26(20):5388-5396. doi: 10.1016/j.bmc.2018.07.024. Epub 2018 Jul 17. Bioorg Med Chem. 2018. PMID: 30293795
Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition.
Ribeiro AG, Almeida SMV, de Oliveira JF, Souza TRCL, Santos KLD, Albuquerque APB, Nogueira MCBL, Carvalho Junior LB, Moura RO, da Silva AC, Pereira VRA, Castro MCAB, Lima MDCA. Ribeiro AG, et al. Among authors: almeida smv. Eur J Med Chem. 2019 Nov 15;182:111592. doi: 10.1016/j.ejmech.2019.111592. Epub 2019 Aug 6. Eur J Med Chem. 2019. PMID: 31421632
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety.
Dos Santos JC, Alves JEF, de Azevedo RDS, de Lima ML, de Oliveira Silva MR, da Silva JG, da Silva JM, de Carvalho Correia AC, do Carmo Alves de Lima M, de Oliveira JF, de Moura RO, de Almeida SMV. Dos Santos JC, et al. Among authors: de almeida smv. Int J Biol Macromol. 2024 Jan;254(Pt 3):127651. doi: 10.1016/j.ijbiomac.2023.127651. Epub 2023 Nov 8. Int J Biol Macromol. 2024. PMID: 37949265
Biochemical and teratogenic effects of a mixture of pyriproxyfen and glyphosate.
Dos Santos Azevedo AS, da Silva JG, Dos Santos JC, de Oliveira Silva MR, de Almeida SMV, de Azevedo RDS, de Sá Leitão Câmara de Araújo M. Dos Santos Azevedo AS, et al. Among authors: de almeida smv. Comp Biochem Physiol C Toxicol Pharmacol. 2024 Jan;275:109766. doi: 10.1016/j.cbpc.2023.109766. Epub 2023 Oct 14. Comp Biochem Physiol C Toxicol Pharmacol. 2024. PMID: 37844749
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation.
Albino SL, da Silva Moura WC, Reis MMLD, Sousa GLS, da Silva PR, de Oliveira MGC, Borges TKDS, Albuquerque LFF, de Almeida SMV, de Lima MDCA, Kuckelhaus SAS, Nascimento IJDS, Junior FJBM, da Silva TG, de Moura RO. Albino SL, et al. Among authors: de almeida smv. Pharmaceuticals (Basel). 2023 Jan 29;16(2):204. doi: 10.3390/ph16020204. Pharmaceuticals (Basel). 2023. PMID: 37259353 Free PMC article.
Interaction study with DNA/HSA, anti-topoisomerase IIα, cytotoxicity and in vitro antiproliferative evaluations and molecular docking of indole-thiosemicarbazone compounds.
Jacob IT, da Cruz Filho IJ, Alves JEF, de Melo Souza F, de Azevedo RDS, Marques DSC, de Lima Souza TRC, Dos Santos KL, da Rocha Pitta MG, de Melo Rêgo MJB, Oliveira JF, Almeida SMV, do Carmo Alves de Lima M. Jacob IT, et al. Among authors: almeida smv. Int J Biol Macromol. 2023 Apr 15;234:123606. doi: 10.1016/j.ijbiomac.2023.123606. Epub 2023 Feb 10. Int J Biol Macromol. 2023. PMID: 36773880
Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine-Thiosemicarbazone Derivatives.
Sousa G, de Almeida MCF, Lócio LL, Dos Santos VL, Bezerra DP, Silva VR, de Almeida SMV, Simon A, Honório TDS, Cabral LM, Castro RN, de Moura RO, Kümmerle AE. Sousa G, et al. Among authors: de almeida smv. Pharmaceuticals (Basel). 2022 Sep 2;15(9):1098. doi: 10.3390/ph15091098. Pharmaceuticals (Basel). 2022. PMID: 36145320 Free PMC article.
32 results