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The SRPK inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl) isonicotinamide (SRPIN340) increases the immune response against metastatic melanoma in mice.
Moreira GA, Caetano MMM, do Vale JA, de Paiva JC, Gonçalves VHS, Almeida AA, Silva LVG, Martim FRG, de Andrade Barros MV, Guimarães GR, de Oliveira Santos L, de Souza APM, Machado-Neves M, Teixeira RR, Silva-Júnior A, Fietto JLR, Boroni M, de Oliveira LL, Bressan GC. Moreira GA, et al. Among authors: almeida aa. Biochem Pharmacol. 2022 Sep;203:115161. doi: 10.1016/j.bcp.2022.115161. Epub 2022 Jul 2. Biochem Pharmacol. 2022. PMID: 35787994 Free article.
Cytotoxic screening of plants from the Brazilian Atlantic Forest has led to the identification of Casearia arborea and Sorocea hilarii as sources of antitumor compounds.
Rodrigues LA, Almeida AA, Agrizii AP, Pacheco N, Carvalho BCR, Zanatta AC, Kohlhoff M, Torres CMME, Bressan GC, Leite JPV. Rodrigues LA, et al. Among authors: almeida aa. Nat Prod Res. 2024 Jun;38(11):1950-1955. doi: 10.1080/14786419.2023.2225689. Epub 2023 Jun 27. Nat Prod Res. 2024. PMID: 37367484
277 results