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mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials.
Feldman RA, Fuhr R, Smolenov I, Mick Ribeiro A, Panther L, Watson M, Senn JJ, Smith M, Almarsson Ӧ, Pujar HS, Laska ME, Thompson J, Zaks T, Ciaramella G. Feldman RA, et al. Vaccine. 2019 May 31;37(25):3326-3334. doi: 10.1016/j.vaccine.2019.04.074. Epub 2019 May 10. Vaccine. 2019. PMID: 31079849 Free article. Clinical Trial.
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.
Hassett KJ, Benenato KE, Jacquinet E, Lee A, Woods A, Yuzhakov O, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, Moore MJ, Senn JJ, Stanton MG, Almarsson Ö, Ciaramella G, Brito LA. Hassett KJ, et al. Mol Ther Nucleic Acids. 2019 Apr 15;15:1-11. doi: 10.1016/j.omtn.2019.01.013. Epub 2019 Feb 7. Mol Ther Nucleic Acids. 2019. PMID: 30785039 Free PMC article.
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity.
Hassett KJ, Higgins J, Woods A, Levy B, Xia Y, Hsiao CJ, Acosta E, Almarsson Ö, Moore MJ, Brito LA. Hassett KJ, et al. J Control Release. 2021 Jul 10;335:237-246. doi: 10.1016/j.jconrel.2021.05.021. Epub 2021 May 18. J Control Release. 2021. PMID: 34019945 Free article.
Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA.
Patel S, Ashwanikumar N, Robinson E, DuRoss A, Sun C, Murphy-Benenato KE, Mihai C, Almarsson Ö, Sahay G. Patel S, et al. Among authors: almarsson o. Nano Lett. 2017 Sep 13;17(9):5711-5718. doi: 10.1021/acs.nanolett.7b02664. Epub 2017 Aug 24. Nano Lett. 2017. PMID: 28836442 Free PMC article.
41 results