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Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome.
Larionov A, Dahlke E, Kunke M, Zanon Rodriguez L, Schiessl IM, Magnin JL, Kern U, Alli AA, Mollet G, Schilling O, Castrop H, Theilig F. Larionov A, et al. Among authors: alli aa. J Cell Mol Med. 2019 Oct;23(10):6543-6553. doi: 10.1111/jcmm.14387. Epub 2019 Jul 31. J Cell Mol Med. 2019. PMID: 31368174 Free PMC article.
The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.
Mistry AC, Wynne BM, Yu L, Tomilin V, Yue Q, Zhou Y, Al-Khalili O, Mallick R, Cai H, Alli AA, Ko B, Mattheyses A, Bao HF, Pochynyuk O, Theilig F, Eaton DC, Hoover RS. Mistry AC, et al. Among authors: alli aa. Biochem J. 2016 Oct 1;473(19):3237-52. doi: 10.1042/BCJ20160312. Epub 2016 Jul 15. Biochem J. 2016. PMID: 27422782 Free PMC article.
Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.
Trac PT, Thai TL, Linck V, Zou L, Greenlee M, Yue Q, Al-Khalili O, Alli AA, Eaton AF, Eaton DC. Trac PT, et al. Among authors: alli aa. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L797-L811. doi: 10.1152/ajplung.00379.2016. Epub 2017 Mar 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28283476 Free PMC article.
ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins.
Montgomery DS, Yu L, Ghazi ZM, Thai TL, Al-Khalili O, Ma HP, Eaton DC, Alli AA. Montgomery DS, et al. Among authors: alli aa. Am J Physiol Cell Physiol. 2017 Jul 1;313(1):C42-C53. doi: 10.1152/ajpcell.00244.2016. Epub 2017 May 3. Am J Physiol Cell Physiol. 2017. PMID: 28468944 Free PMC article.
Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity.
Jella KK, Yu L, Yue Q, Friedman D, Duke BJ, Alli AA. Jella KK, et al. Among authors: alli aa. PLoS One. 2016 Nov 1;11(11):e0165763. doi: 10.1371/journal.pone.0165763. eCollection 2016. PLoS One. 2016. PMID: 27802315 Free PMC article.
72 results