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Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching.
Commun Chem. 2023 Aug 19;6(1):168. doi: 10.1038/s42004-023-00982-7.
Commun Chem. 2023.
PMID: 37598249
Free PMC article.
Describing Complex Structure-Function Relationships in Biomolecules at Equilibrium.
Allert MJ, Hellinga HW.
Allert MJ, et al.
J Mol Biol. 2020 Mar 27;432(7):1926-1951. doi: 10.1016/j.jmb.2019.12.039. Epub 2020 Jan 12.
J Mol Biol. 2020.
PMID: 31940471
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Harnessing Environmental Ca2+ for Extracellular Protein Thermostabilization.
Allert MJ, Hellinga HW.
Allert MJ, et al.
Biochemistry. 2020 Oct 6;59(39):3725-3740. doi: 10.1021/acs.biochem.0c00449. Epub 2020 Sep 24.
Biochemistry. 2020.
PMID: 32915552
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Discovery of Thermostable, Fluorescently Responsive Glucose Biosensors by Structure-Assisted Function Extrapolation.
Allert MJ, Hellinga HW.
Allert MJ, et al.
Biochemistry. 2022 Feb 15;61(4):276-293. doi: 10.1021/acs.biochem.1c00738. Epub 2022 Jan 27.
Biochemistry. 2022.
PMID: 35084821
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Computational design of receptors for an organophosphate surrogate of the nerve agent soman.
Allert M, Rizk SS, Looger LL, Hellinga HW.
Allert M, et al.
Proc Natl Acad Sci U S A. 2004 May 25;101(21):7907-12. doi: 10.1073/pnas.0401309101. Epub 2004 May 17.
Proc Natl Acad Sci U S A. 2004.
PMID: 15148405
Free PMC article.
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Local encoding of computationally designed enzyme activity.
Allert M, Dwyer MA, Hellinga HW.
Allert M, et al.
J Mol Biol. 2007 Feb 23;366(3):945-53. doi: 10.1016/j.jmb.2006.12.002. Epub 2006 Dec 5.
J Mol Biol. 2007.
PMID: 17196220
Free PMC article.
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The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog.
Cuneo MJ, Tian Y, Allert M, Hellinga HW.
Cuneo MJ, et al. Among authors: allert m.
BMC Struct Biol. 2008 Mar 28;8:20. doi: 10.1186/1472-6807-8-20.
BMC Struct Biol. 2008.
PMID: 18373848
Free PMC article.
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Multifactorial determinants of protein expression in prokaryotic open reading frames.
Allert M, Cox JC, Hellinga HW.
Allert M, et al.
J Mol Biol. 2010 Oct 8;402(5):905-18. doi: 10.1016/j.jmb.2010.08.010. Epub 2010 Aug 18.
J Mol Biol. 2010.
PMID: 20727358
Free PMC article.
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