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Page 1
Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies.
Slatter DA, Percy CL, Allen-Redpath K, Gajsiewicz JM, Brooks NJ, Clayton A, Tyrrell VJ, Rosas M, Lauder SN, Watson A, Dul M, Garcia-Diaz Y, Aldrovandi M, Heurich M, Hall J, Morrissey JH, Lacroix-Desmazes S, Delignat S, Jenkins PV, Collins PW, O'Donnell VB. Slatter DA, et al. Among authors: allen redpath k. JCI Insight. 2018 Mar 22;3(6):e98459. doi: 10.1172/jci.insight.98459. JCI Insight. 2018. PMID: 29563336 Free PMC article.
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.
Lauder SN, Allen-Redpath K, Slatter DA, Aldrovandi M, O'Connor A, Farewell D, Percy CL, Molhoek JE, Rannikko S, Tyrrell VJ, Ferla S, Milne GL, Poole AW, Thomas CP, Obaji S, Taylor PR, Jones SA, de Groot PG, Urbanus RT, Hörkkö S, Uderhardt S, Ackermann J, Vince Jenkins P, Brancale A, Krönke G, Collins PW, O'Donnell VB. Lauder SN, et al. Among authors: allen redpath k. Sci Signal. 2017 Nov 28;10(507):eaan2787. doi: 10.1126/scisignal.aan2787. Sci Signal. 2017. PMID: 29184033 Free PMC article.
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Allen-Redpath K, Aldrovandi M, Lauder SN, Gketsopoulou A, Tyrrell VJ, Slatter DA, Andrews R, Watkins WJ, Atkinson G, McNeill E, Gilfedder A, Protty M, Burston J, Johnson SRC, Rodrigues PRS, Jones DO, Lee R, Handa A, Channon K, Obaji S, Alvarez-Jarreta J, Krönke G, Ackermann J, Jenkins PV, Collins PW, O'Donnell VB. Allen-Redpath K, et al. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8038-8047. doi: 10.1073/pnas.1814409116. Epub 2019 Apr 3. Proc Natl Acad Sci U S A. 2019. PMID: 30944221 Free PMC article.
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease.
Hajeyah AA, Protty MB, Paul D, Costa D, Omidvar N, Morgan B, Iwasaki Y, McGill B, Jenkins PV, Yousef Z, Allen-Redpath K, Soyama S, Choudhury A, Mitra R, Yaqoob P, Morrissey JH, Collins PW, O'Donnell VB. Hajeyah AA, et al. Among authors: allen redpath k. J Lipid Res. 2024 Jan;65(1):100484. doi: 10.1016/j.jlr.2023.100484. Epub 2023 Dec 14. J Lipid Res. 2024. PMID: 38103786 Free PMC article.
Plasma zinc's alter ego is a low-molecular-weight humoral factor.
Ou O, Allen-Redpath K, Urgast D, Gordon MJ, Campbell G, Feldmann J, Nixon GF, Mayer CD, Kwun IS, Beattie JH. Ou O, et al. Among authors: allen redpath k. FASEB J. 2013 Sep;27(9):3672-82. doi: 10.1096/fj.13-228791. Epub 2013 May 31. FASEB J. 2013. PMID: 23729592
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