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Transversions have larger regulatory effects than transitions.
Guo C, McDowell IC, Nodzenski M, Scholtens DM, Allen AS, Lowe WL, Reddy TE. Guo C, et al. Among authors: allen as. BMC Genomics. 2017 May 19;18(1):394. doi: 10.1186/s12864-017-3785-4. BMC Genomics. 2017. PMID: 28525990 Free PMC article.
Human genome-wide measurement of drug-responsive regulatory activity.
Johnson GD, Barrera A, McDowell IC, D'Ippolito AM, Majoros WH, Vockley CM, Wang X, Allen AS, Reddy TE. Johnson GD, et al. Among authors: allen as. Nat Commun. 2018 Dec 21;9(1):5317. doi: 10.1038/s41467-018-07607-x. Nat Commun. 2018. PMID: 30575722 Free PMC article.
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS.
Gelfman S, Dugger S, de Araujo Martins Moreno C, Ren Z, Wolock CJ, Shneider NA, Phatnani H, Cirulli ET, Lasseigne BN, Harris T, Maniatis T, Rouleau GA, Brown RH Jr, Gitler AD, Myers RM, Petrovski S, Allen A, Goldstein DB, Harms MB. Gelfman S, et al. Genome Res. 2019 May;29(5):809-818. doi: 10.1101/gr.243592.118. Epub 2019 Apr 2. Genome Res. 2019. PMID: 30940688 Free PMC article.
Bayesian estimation of genetic regulatory effects in high-throughput reporter assays.
Majoros WH, Kim YS, Barrera A, Li F, Wang X, Cunningham SJ, Johnson GD, Guo C, Lowe WL, Scholtens DM, Hayes MG, Reddy TE, Allen AS. Majoros WH, et al. Among authors: allen as. Bioinformatics. 2020 Jan 15;36(2):331-338. doi: 10.1093/bioinformatics/btz545. Bioinformatics. 2020. PMID: 31368479 Free PMC article.
141 results