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ACE2 binding is an ancestral and evolvable trait of sarbecoviruses.
Starr TN, Zepeda SK, Walls AC, Greaney AJ, Alkhovsky S, Veesler D, Bloom JD. Starr TN, et al. Among authors: alkhovsky s. Nature. 2022 Mar;603(7903):913-918. doi: 10.1038/s41586-022-04464-z. Epub 2022 Feb 3. Nature. 2022. PMID: 35114688 Free PMC article.
[Source of the COVID-19 pandemic: ecology and genetics of coronaviruses (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (subgenus Sarbecovirus), and MERS-CoV (subgenus Merbecovirus).].
Lvov DK, Alkhovsky SV. Lvov DK, et al. Among authors: alkhovsky sv. Vopr Virusol. 2020;65(2):62-70. doi: 10.36233/0507-4088-2020-65-2-62-70. Vopr Virusol. 2020. PMID: 32515561 Review. Russian.
The main mechanism of adaptation of zoonotic betacoronaviruses to humans is to changes in the receptor-binding domain of surface protein (S), as a result of which it gains the ability to bind human cellular receptors of epithelial cells in respiratory and gastrointestinal …
The main mechanism of adaptation of zoonotic betacoronaviruses to humans is to changes in the receptor-binding domain of surface protein ( …
Reorganization and expansion of the nidoviral family Arteriviridae.
Kuhn JH, Lauck M, Bailey AL, Shchetinin AM, Vishnevskaya TV, Bào Y, Ng TF, LeBreton M, Schneider BS, Gillis A, Tamoufe U, Diffo Jle D, Takuo JM, Kondov NO, Coffey LL, Wolfe ND, Delwart E, Clawson AN, Postnikova E, Bollinger L, Lackemeyer MG, Radoshitzky SR, Palacios G, Wada J, Shevtsova ZV, Jahrling PB, Lapin BA, Deriabin PG, Dunowska M, Alkhovsky SV, Rogers J, Friedrich TC, O'Connor DH, Goldberg TL. Kuhn JH, et al. Among authors: alkhovsky sv. Arch Virol. 2016 Mar;161(3):755-68. doi: 10.1007/s00705-015-2672-z. Epub 2015 Nov 25. Arch Virol. 2016. PMID: 26608064 Free PMC article.
Exploiting the Legacy of the Arbovirus Hunters.
Vasilakis N, Tesh RB, Popov VL, Widen SG, Wood TG, Forrester NL, Gonzalez JP, Saluzzo JF, Alkhovsky S, Lam SK, Mackenzie JS, Walker PJ. Vasilakis N, et al. Among authors: alkhovsky s. Viruses. 2019 May 23;11(5):471. doi: 10.3390/v11050471. Viruses. 2019. PMID: 31126128 Free PMC article. Review.
36 results