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Identification of Gain and Loss of Function Missense Variants in MRGPRX2's Transmembrane and Intracellular Domains for Mast Cell Activation by Substance P.
Int J Mol Sci. 2019 Oct 23;20(21):5247. doi: 10.3390/ijms20215247.
Int J Mol Sci. 2019.
PMID: 31652731
Free PMC article.
Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant.
Alkanfari I, Gupta K, Jahan T, Ali H.
Alkanfari I, et al.
J Immunol. 2018 Jul 15;201(2):343-349. doi: 10.4049/jimmunol.1701793. Epub 2018 May 23.
J Immunol. 2018.
PMID: 29794017
Free PMC article.
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Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs.
Alkanfari I, Freeman KB, Roy S, Jahan T, Scott RW, Ali H.
Alkanfari I, et al.
Cells. 2019 Apr 3;8(4):311. doi: 10.3390/cells8040311.
Cells. 2019.
PMID: 30987258
Free PMC article.
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Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells.
Chaki S, Alkanfari I, Roy S, Amponnawarat A, Hui Y, Oskeritzian CA, Ali H.
Chaki S, et al. Among authors: alkanfari i.
Front Immunol. 2022 Jan 20;12:803335. doi: 10.3389/fimmu.2021.803335. eCollection 2021.
Front Immunol. 2022.
PMID: 35126366
Free PMC article.
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Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by β-Arrestin 2.
Roy S, Alkanfari I, Chaki S, Ali H.
Roy S, et al. Among authors: alkanfari i.
J Invest Dermatol. 2022 Nov;142(11):2988-2997.e3. doi: 10.1016/j.jid.2022.05.005. Epub 2022 May 26.
J Invest Dermatol. 2022.
PMID: 35644498
Free PMC article.
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