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Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5,5-diphenylimidazolidine-2,4-dione derivatives: Molecular docking studies.
Alkahtani HM, Alanazi MM, Aleanizy FS, Alqahtani FY, Alhoshani A, Alanazi FE, Almehizia AA, Abdalla AN, Alanazi MG, El-Azab AS, Abdel-Aziz AA. Alkahtani HM, et al. Saudi Pharm J. 2019 Jul;27(5):682-693. doi: 10.1016/j.jsps.2019.04.003. Epub 2019 Apr 3. Saudi Pharm J. 2019. PMID: 31297023 Free PMC article.
Synthesis, anticancer and apoptosis-inducing activities of quinazoline-isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.
El-Azab AS, Al-Dhfyan A, Abdel-Aziz AA, Abou-Zeid LA, Alkahtani HM, Al-Obaid AM, Al-Gendy MA. El-Azab AS, et al. Among authors: alkahtani hm. J Enzyme Inhib Med Chem. 2017 Dec;32(1):935-944. doi: 10.1080/14756366.2017.1344981. J Enzyme Inhib Med Chem. 2017. PMID: 28718672 Free PMC article.
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.
Eldehna WM, Nocentini A, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Reda AM, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: alkahtani hm. Bioorg Chem. 2018 Dec;81:425-432. doi: 10.1016/j.bioorg.2018.09.007. Epub 2018 Sep 7. Bioorg Chem. 2018. PMID: 30219719
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
Eldehna WM, Abo-Ashour MF, Berrino E, Vullo D, Ghabbour HA, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Alharbi A, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: alkahtani hm. Bioorg Chem. 2019 Mar;83:549-558. doi: 10.1016/j.bioorg.2018.11.014. Epub 2018 Nov 14. Bioorg Chem. 2019. PMID: 30471577
Paclitaxel.
Alqahtani FY, Aleanizy FS, El Tahir E, Alkahtani HM, AlQuadeib BT. Alqahtani FY, et al. Among authors: alkahtani hm. Profiles Drug Subst Excip Relat Methodol. 2019;44:205-238. doi: 10.1016/bs.podrm.2018.11.001. Epub 2019 Apr 22. Profiles Drug Subst Excip Relat Methodol. 2019. PMID: 31029218
Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.
Abdelrahman MA, Eldehna WM, Nocentini A, Bua S, Al-Rashood ST, Hassan GS, Bonardi A, Almehizia AA, Alkahtani HM, Alharbi A, Gratteri P, Supuran CT. Abdelrahman MA, et al. Among authors: alkahtani hm. Int J Mol Sci. 2019 May 20;20(10):2484. doi: 10.3390/ijms20102484. Int J Mol Sci. 2019. PMID: 31137489 Free PMC article.
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