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Cellular Senescence: Aging, Cancer, and Injury.
Calcinotto A, Kohli J, Zagato E, Pellegrini L, Demaria M, Alimonti A. Calcinotto A, et al. Among authors: alimonti a. Physiol Rev. 2019 Apr 1;99(2):1047-1078. doi: 10.1152/physrev.00020.2018. Physiol Rev. 2019. PMID: 30648461 Free article. Review.
Pro-senescence therapy for cancer treatment.
Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Nardella C, et al. Among authors: alimonti a. Nat Rev Cancer. 2011 Jun 24;11(7):503-11. doi: 10.1038/nrc3057. Nat Rev Cancer. 2011. PMID: 21701512 Review.
Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer.
Di Mitri D, Toso A, Chen JJ, Sarti M, Pinton S, Jost TR, D'Antuono R, Montani E, Garcia-Escudero R, Guccini I, Da Silva-Alvarez S, Collado M, Eisenberger M, Zhang Z, Catapano C, Grassi F, Alimonti A. Di Mitri D, et al. Among authors: alimonti a. Nature. 2014 Nov 6;515(7525):134-7. doi: 10.1038/nature13638. Epub 2014 Aug 24. Nature. 2014. PMID: 25156255
Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.
Revandkar A, Perciato ML, Toso A, Alajati A, Chen J, Gerber H, Dimitrov M, Rinaldi A, Delaleu N, Pasquini E, D'Antuono R, Pinton S, Losa M, Gnetti L, Arribas A, Fraering P, Bertoni F, Nepveu A, Alimonti A. Revandkar A, et al. Among authors: alimonti a. Nat Commun. 2016 Dec 12;7:13719. doi: 10.1038/ncomms13719. Nat Commun. 2016. PMID: 27941799 Free PMC article.
IL-23 secreted by myeloid cells drives castration-resistant prostate cancer.
Calcinotto A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, De Bernardis G, Losa M, Mirenda M, Pasquini E, Rinaldi A, Sumanasuriya S, Lambros MB, Neeb A, Lucianò R, Bravi CA, Nava-Rodrigues D, Dolling D, Prayer-Galetti T, Ferreira A, Briganti A, Esposito A, Barry S, Yuan W, Sharp A, de Bono J, Alimonti A. Calcinotto A, et al. Among authors: alimonti a. Nature. 2018 Jul;559(7714):363-369. doi: 10.1038/s41586-018-0266-0. Epub 2018 Jun 27. Nature. 2018. PMID: 29950727 Free PMC article.
Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.
Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, Gil V, Boysen G, Losa M, Mosole S, Pasquini E, D'Antuono R, Masetti M, Zagato E, Chiorino G, Ostano P, Rinaldi A, Gnetti L, Graupera M, Martins Figueiredo Fonseca AR, Pereira Mestre R, Waugh D, Barry S, De Bono J, Alimonti A. Di Mitri D, et al. Among authors: alimonti a. Cell Rep. 2019 Aug 20;28(8):2156-2168.e5. doi: 10.1016/j.celrep.2019.07.068. Cell Rep. 2019. PMID: 31433989 Free PMC article.
Targeting PML in triple negative breast cancer elicits growth suppression and senescence.
Arreal L, Piva M, Fernández S, Revandkar A, Schaub-Clerigué A, Villanueva J, Zabala-Letona A, Pujana M, Astobiza I, Cortazar AR, Hermanova I, Bozal-Basterra L, Arruabarrena-Aristorena A, Crespo JR, Valcarcel-Jimenez L, Zúñiga-García P, Canals F, Torrano V, Barrio R, Sutherland JD, Alimonti A, Martin-Martin N, Carracedo A. Arreal L, et al. Among authors: alimonti a. Cell Death Differ. 2020 Apr;27(4):1186-1199. doi: 10.1038/s41418-019-0407-5. Epub 2019 Oct 1. Cell Death Differ. 2020. PMID: 31570853 Free PMC article.
216 results