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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J. Wiley CD, et al. Among authors: alimirah f. Cell Metab. 2021 Jun 1;33(6):1124-1136.e5. doi: 10.1016/j.cmet.2021.03.008. Epub 2021 Apr 2. Cell Metab. 2021. PMID: 33811820 Free PMC article.
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells.
Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P. Wiley CD, et al. Among authors: alimirah f. Cell Rep. 2019 Sep 24;28(13):3329-3337.e5. doi: 10.1016/j.celrep.2019.08.049. Cell Rep. 2019. PMID: 31553904 Free PMC article.
Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis.
Wiley CD, Brumwell AN, Davis SS, Jackson JR, Valdovinos A, Calhoun C, Alimirah F, Castellanos CA, Ruan R, Wei Y, Chapman HA, Ramanathan A, Campisi J, Jourdan Le Saux C. Wiley CD, et al. Among authors: alimirah f. JCI Insight. 2019 Dec 19;4(24):e130056. doi: 10.1172/jci.insight.130056. JCI Insight. 2019. PMID: 31687975 Free PMC article.
Cellular Senescence Promotes Skin Carcinogenesis through p38MAPK and p44/42MAPK Signaling.
Alimirah F, Pulido T, Valdovinos A, Alptekin S, Chang E, Jones E, Diaz DA, Flores J, Velarde MC, Demaria M, Davalos AR, Wiley CD, Limbad C, Desprez PY, Campisi J. Alimirah F, et al. Cancer Res. 2020 Sep 1;80(17):3606-3619. doi: 10.1158/0008-5472.CAN-20-0108. Epub 2020 Jul 8. Cancer Res. 2020. PMID: 32641409 Free PMC article.
Oncogenic senescence: a multi-functional perspective.
Baker DJ, Alimirah F, van Deursen JM, Campisi J, Hildesheim J. Baker DJ, et al. Among authors: alimirah f. Oncotarget. 2017 Apr 18;8(16):27661-27672. doi: 10.18632/oncotarget.15742. Oncotarget. 2017. PMID: 28416761 Free PMC article.
Systemic induction of senescence in young mice after single heterochronic blood exchange.
Jeon OH, Mehdipour M, Gil TH, Kang M, Aguirre NW, Robinson ZR, Kato C, Etienne J, Lee HG, Alimirah F, Walavalkar V, Desprez PY, Conboy MJ, Campisi J, Conboy IM. Jeon OH, et al. Among authors: alimirah f. Nat Metab. 2022 Aug;4(8):995-1006. doi: 10.1038/s42255-022-00609-6. Epub 2022 Jul 28. Nat Metab. 2022. PMID: 35902645 Free PMC article.
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Demaria M, O'Leary MN, Chang J, Shao L, Liu S, Alimirah F, Koenig K, Le C, Mitin N, Deal AM, Alston S, Academia EC, Kilmarx S, Valdovinos A, Wang B, de Bruin A, Kennedy BK, Melov S, Zhou D, Sharpless NE, Muss H, Campisi J. Demaria M, et al. Among authors: alimirah f. Cancer Discov. 2017 Feb;7(2):165-176. doi: 10.1158/2159-8290.CD-16-0241. Epub 2016 Dec 15. Cancer Discov. 2017. PMID: 27979832 Free PMC article.
30 results